Methyl 3-(4-(2-hydroxyethylcarbamoyl)benzyl)-1,4-dihydro-7-methyl-4-oxo-1-phenyl-1,8-naphthyridine-2-carboxylate

• 常用名: Methyl 3-(4-(2-hydroxyethylcarbamoyl)benzyl)-1,4-dihydro-7-methyl-4-oxo-1-phenyl-1,8-naphthyridine-2-carboxylate
• 英文名: Methyl 3-(4-(2-hydroxyethylcarbamoyl)benzyl)-1,4-dihydro-7-methyl-4-oxo-1-phenyl-1,8-naphthyridine-2-carboxylate
• CAS号: 1080673-91-1
• 分子量: 471.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₇H₂₅N₃O₅
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: Methyl 3-(4-(2-hydroxyethylcarbamoyl)benzyl)-1,4-dihydro-7-methyl-4-oxo-1-phenyl-1,8-naphthyridine-2-carboxylate

物理化学性质

• 分子式: C₂₇H₂₅N₃O₅
• 分子量: 471.5
• InChIKey: AIPARAKSAHWEMY-UHFFFAOYSA-N
• SMILES: CC1=NC2=C(C=C1)C(=O)C(=C(N2C3=CC=CC=C3)C(=O)OC)CC4=CC=C(C=C4)C(=O)NCCO

靶点实验

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实验名称：Inhibition of JNK in human SW1353 assessed as inhibition of TNFalpha-inuced c-Jun pho... 来源：ChEMBL 靶标：Mitogen-activated protein kinase 9 External Id：CHEMBL2215642

实验名称：Ratio of IC50 for human JNK1 alpha1 in presence of 40% human serum albumin to IC50 fo... 来源：ChEMBL 靶标：Mitogen-activated protein kinase 8 External Id：CHEMBL2215643

实验名称：Efflux ratio of permeability from apical to basal to basal to apical side of human Ca... 来源：ChEMBL 靶标：Caco-2 External Id：CHEMBL2215640

实验名称：Solubility of the compound in phosphate buffer at pH 6.4 来源：ChEMBL 靶标：N/A External Id：CHEMBL2215641

实验名称：Inhibition of human JNK2 alpha2 using GST-tagged ATF2 as substrate and [gamma33P]ATP ... 来源：ChEMBL 靶标：Mitogen-activated protein kinase 9 External Id：CHEMBL2215644

实验名称：Inhibition of human JNK1 alpha1 using GST-tagged ATF2 as substrate and [gamma33P]ATP ... 来源：ChEMBL 靶标：Mitogen-activated protein kinase 8 External Id：CHEMBL2216094

实验名称：Permeability of the compound from apical to basal side of human Caco2 cells 来源：ChEMBL 靶标：Caco-2 External Id：CHEMBL2215639

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