Methyl 7-fluoro-1,4-dihydro-4-oxo-1-phenyl-3-[[4-(1-piperazinylsulfonyl)phenyl]methyl]-2-quinolinecarboxylate

• 常用名: Methyl 7-fluoro-1,4-dihydro-4-oxo-1-phenyl-3-[[4-(1-piperazinylsulfonyl)phenyl]methyl]-2-quinolinecarboxylate
• 英文名: Methyl 7-fluoro-1,4-dihydro-4-oxo-1-phenyl-3-[[4-(1-piperazinylsulfonyl)phenyl]methyl]-2-quinolinecarboxylate
• CAS号: 1081504-62-2
• 分子量: 535.6
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₈H₂₆FN₃O₅S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: Methyl 7-fluoro-1,4-dihydro-4-oxo-1-phenyl-3-[[4-(1-piperazinylsulfonyl)phenyl]methyl]-2-quinolinecarboxylate

物理化学性质

• 分子式: C₂₈H₂₆FN₃O₅S
• 分子量: 535.6
• InChIKey: RXFQQWFTSGTXMV-UHFFFAOYSA-N
• SMILES: COC(=O)c1c(Cc2ccc(S(=O)(=O)N3CCNCC3)cc2)c(=O)c2ccc(F)cc2n1-c1ccccc1

靶点实验

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实验名称：Inhibition of JNK in human SW1353 assessed as inhibition of TNFalpha-inuced c-Jun pho... 来源：ChEMBL 靶标：Mitogen-activated protein kinase 9 External Id：CHEMBL2215642

实验名称：Ratio of IC50 for human JNK1 alpha1 in presence of 40% human serum albumin to IC50 fo... 来源：ChEMBL 靶标：Mitogen-activated protein kinase 8 External Id：CHEMBL2215643

实验名称：Efflux ratio of permeability from apical to basal to basal to apical side of human Ca... 来源：ChEMBL 靶标：Caco-2 External Id：CHEMBL2215640

实验名称：Solubility of the compound in phosphate buffer at pH 6.4 来源：ChEMBL 靶标：N/A External Id：CHEMBL2215641

实验名称：Inhibition of human JNK2 alpha2 using GST-tagged ATF2 as substrate and [gamma33P]ATP ... 来源：ChEMBL 靶标：Mitogen-activated protein kinase 9 External Id：CHEMBL2215644

实验名称：Inhibition of human JNK1 alpha1 using GST-tagged ATF2 as substrate and [gamma33P]ATP ... 来源：ChEMBL 靶标：Mitogen-activated protein kinase 8 External Id：CHEMBL2216094

实验名称：Permeability of the compound from apical to basal side of human Caco2 cells 来源：ChEMBL 靶标：Caco-2 External Id：CHEMBL2215639

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