N-(2,6-Difluorophenyl)-3-[8-fluoro-3-[2-[[4-[4-[4-(2-fluoroethyl)-1-piperazinyl]-1-piperidinyl]-2-methoxyphenyl]amino]-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl]benzamide

• 常用名: N-(2,6-Difluorophenyl)-3-[8-fluoro-3-[2-[[4-[4-[4-(2-fluoroethyl)-1-piperazinyl]-1-piperidinyl]-2-methoxyphenyl]amino]-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl]benzamide
• 英文名: N-(2,6-Difluorophenyl)-3-[8-fluoro-3-[2-[[4-[4-[4-(2-fluoroethyl)-1-piperazinyl]-1-piperidinyl]-2-methoxyphenyl]amino]-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl]benzamide
• CAS号: 1089282-55-2
• 分子量: 779.8
• 密度: N/A
• 沸点: N/A
• 分子式: C₄₂H₄₁F₄N₉O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-(2,6-Difluorophenyl)-3-[8-fluoro-3-[2-[[4-[4-[4-(2-fluoroethyl)-1-piperazinyl]-1-piperidinyl]-2-methoxyphenyl]amino]-4-pyrimidinyl]imidazo[1,2-a]pyridin-2-yl]benzamide

物理化学性质

• 分子式: C₄₂H₄₁F₄N₉O₂
• 分子量: 779.8
• InChIKey: DWCCBCDWBJKECP-UHFFFAOYSA-N
• SMILES: COc1cc(N2CCC(N3CCN(CCF)CC3)CC2)ccc1Nc1nccc(-c2c(-c3cccc(C(=O)Nc4c(F)cccc4F)c3)nc3c(F)cccn23)n1

靶点实验

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实验名称：Inhibition of human GST-rTEV-tagged IGF1R (957 to 1367 residues) expressed in baculov... 来源：ChEMBL 靶标：Insulin-like growth factor 1 receptor External Id：CHEMBL3882757

实验名称：Inhibition of human GST-rTEV-tagged insulin receptor (979 to 1382 residues) expressed... 来源：ChEMBL 靶标：Insulin receptor External Id：CHEMBL3882758

实验名称：Inhibition of IGF1-induced human IGF1R autophosphorylation expressed in mouse NIH-3T3... 来源：ChEMBL 靶标：Insulin-like growth factor 1 receptor External Id：CHEMBL3883019

实验名称：Inhibition of insulin-induced human insulin receptor autophosphorylation expressed in... 来源：ChEMBL 靶标：Insulin receptor External Id：CHEMBL3883020

实验名称：Inhibition of recombinant human full length EGFR expressed in baculovirus expression ... 来源：ChEMBL 靶标：Epidermal growth factor receptor External Id：CHEMBL3882759

实验名称：Inhibition of recombinant human full length ErbB2 expressed in baculovirus expression... 来源：ChEMBL 靶标：Receptor tyrosine-protein kinase erbB-2 External Id：CHEMBL3882760

实验名称：Cytotoxicity against human COLO205 cells assessed as cell growth inhibition after 72 ... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3882761

实验名称：Cytotoxicity against human NCI-H929 cells assessed as cell growth inhibition after 72... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3882762

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