N-(2,6-difluorophenyl)-5-(3-{2-[(5-ethyl-2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide

• 常用名: N-(2,6-difluorophenyl)-5-(3-{2-[(5-ethyl-2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
• 英文名: N-(2,6-difluorophenyl)-5-(3-{2-[(5-ethyl-2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide
• CAS号: 1089282-92-7
• 分子量: 795.9
• 密度: N/A
• 沸点: N/A
• 分子式: C₄₂H₄₃F₂N₇O₅S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-(2,6-difluorophenyl)-5-(3-{2-[(5-ethyl-2-(methyloxy)-4-{4-[2-(methylsulfonyl)ethyl]-1-piperidinyl}phenyl)amino]-4-pyrimidinyl}imidazo[1,2-a]pyridin-2-yl)-2-(methyloxy)benzamide

物理化学性质

• 分子式: C₄₂H₄₃F₂N₇O₅S
• 分子量: 795.9
• InChIKey: GMZFFCITNDNEBF-UHFFFAOYSA-N
• SMILES: CCc1cc(Nc2nccc(-c3c(-c4ccc(OC)c(C(=O)Nc5c(F)cccc5F)c4)nc4ccccn34)n2)c(OC)cc1N1CCC(CCS(C)(=O)=O)CC1

靶点实验

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实验名称：Inhibition of human GST-rTEV-tagged insulin receptor (979 to 1382 residues) expressed... 来源：ChEMBL 靶标：Insulin receptor External Id：CHEMBL3882758

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实验名称：Inhibition of insulin-induced human insulin receptor autophosphorylation expressed in... 来源：ChEMBL 靶标：Insulin receptor External Id：CHEMBL3883020

实验名称：Inhibition of recombinant human full length EGFR expressed in baculovirus expression ... 来源：ChEMBL 靶标：Epidermal growth factor receptor External Id：CHEMBL3882759

实验名称：Inhibition of recombinant human full length ErbB2 expressed in baculovirus expression... 来源：ChEMBL 靶标：Receptor tyrosine-protein kinase erbB-2 External Id：CHEMBL3882760

实验名称：Cytotoxicity against human COLO205 cells assessed as cell growth inhibition after 72 ... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3882761

实验名称：Cytotoxicity against human NCI-H929 cells assessed as cell growth inhibition after 72... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3882762

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