N-[5-({2-[(cyclopropylcarbonyl)amino][1,2,4]triazolo[1,5-a]pyridin-6-yl}oxy)-2-fluorophenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide

• 常用名: N-[5-({2-[(cyclopropylcarbonyl)amino][1,2,4]triazolo[1,5-a]pyridin-6-yl}oxy)-2-fluorophenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide
• 英文名: N-[5-({2-[(cyclopropylcarbonyl)amino][1,2,4]triazolo[1,5-a]pyridin-6-yl}oxy)-2-fluorophenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide
• CAS号: 1092391-56-4
• 分子量: 449.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₂H₂₀FN₇O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-[5-({2-[(cyclopropylcarbonyl)amino][1,2,4]triazolo[1,5-a]pyridin-6-yl}oxy)-2-fluorophenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide

物理化学性质

• 分子式: C₂₂H₂₀FN₇O₃
• 分子量: 449.4
• InChIKey: HSKISFLIRPOYCF-UHFFFAOYSA-N
• SMILES: CC1=NN(C(=C1)C(=O)NC2=C(C=CC(=C2)OC3=CN4C(=NC(=N4)NC(=O)C5CC5)C=C3)F)C

靶点实验

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实验名称：Antitumor activity against human DU145 cells xenografted in athymic BALB/cA Jcl-nu/nu... 来源：ChEMBL 靶标：DU-145 External Id：CHEMBL2410710

实验名称：Toxicity in athymic BALB/cA Jcl-nu/nu mouse xenografted with human DU145 cells assess... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2410705

实验名称：Inhibition of human VEGFR2 using biotinylated poly-GluTyr as substrate by AlphaScreen... 来源：ChEMBL 靶标：Vascular endothelial growth factor receptor 2 External Id：CHEMBL2410842

实验名称：Antiproliferative activity against VEGF-treated HUVEC after 5 days by WST-8 assay 来源：ChEMBL 靶标：HUVEC External Id：CHEMBL2410841

实验名称：Toxicity in athymic BALB/cA Jcl-nu/nu mouse xenografted with human DU145 cells assess... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2410704

实验名称：Toxicity in athymic BALB/cA Jcl-nu/nu mouse xenografted with human A549 cells assesse... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2410703

实验名称：Kinetic solubility of the compound in 2nd fluid of Disintegration Test of the Japanes... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2410840

实验名称：Toxicity in athymic BALB/cA Jcl-nu/nu mouse xenografted with human A549 cells assesse... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2410702

实验名称：Antitumor activity against human DU145 cells xenografted in athymic BALB/cA Jcl-nu/nu... 来源：ChEMBL 靶标：DU-145 External Id：CHEMBL2410709

实验名称：Antitumor activity against human A549 cells xenografted in athymic BALB/cA Jcl-nu/nu ... 来源：ChEMBL 靶标：A549 External Id：CHEMBL2410708

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