CI-966

• 常用名: CI-966
• 英文名: CI-966
• CAS号: 110283-79-9
• 分子量: 473.40800
• 密度: 1.34g/cm3
• 沸点: 514.1ºC at 760mmHg
• 分子式: C₂₃H₂₁F₆NO₃
• 熔点: N/A
• 闪点: 264.7ºC

CI-966用途

CI-966 (PD 126141) is a potent, selective inhibitor of the GABA transporter GAT-1 with IC50 of 0.26 and 1.2 uM for human and rat GAT-1, respectively.

CI-966名称

• 英文名: 1-[2-[bis[4-(trifluoromethyl)phenyl]methoxy]ethyl]-3,6-dihydro-2H-pyridine-5-carboxylic acid

CI-966物理化学性质

• 密度: 1.34g/cm3
• 沸点: 514.1ºC at 760mmHg
• 分子式: C₂₃H₂₁F₆NO₃
• 分子量: 473.40800
• 闪点: 264.7ºC
• 精确质量: 473.14300
• PSA: 49.77000
• LogP: 5.48480
• InChIKey: CMHQDSBIBSKHFP-UHFFFAOYSA-N
• SMILES: O=C(O)C1=CCCN(CCOC(c2ccc(C(F)(F)F)cc2)c2ccc(C(F)(F)F)cc2)C1
• 蒸汽压: 2.16E-11mmHg at 25°C
• 折射率: 1.517
• 储存条件: 2-8°C，密封，干燥

CI-966靶点实验

查看更多实验

实验名称：Primary qHTS for small molecule stabilizers of the endoplasmic reticulum resident pro... 来源：NCGC 靶标：N/A External Id：SERCaMPGLuc-p1-antagonist

实验名称：Inhibitory activity against rat GABA transporter-2 (rGAT2) 来源：ChEMBL 靶标：Sodium- and chloride-dependent GABA transporter 2 External Id：CHEMBL809055

实验名称：Cellular viability qHTS for adrenocortical cancer (ACC) cell line SW-13 来源：NCGC 靶标：N/A External Id：ACC-ATC-p1-SW13-72hr

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1100

实验名称：qHTS for Inhibitors of human tyrosyl-DNA phosphodiesterase 1 (TDP1): qHTS in cells in... 来源：NCGC 靶标：TDP1 protein [Homo sapiens] External Id：TDP1101

实验名称：Cellular viability qHTS for adrenocortical cancer (ACC) cell line NCI-H295R 来源：NCGC 靶标：N/A External Id：ACC-ATC-p1-H295R-72hr

实验名称：Cytotoxicity counterscreen for inhibitors of SARS-CoV-2 cell entry 来源：NCGC 靶标：N/A External Id：TRND-SARS-CoV-2-cytotox-48hr

实验名称：Primary qHTS to identify inhibitors of SARS-CoV-2 cell entry 来源：NCGC External Id：TRND-SARS-CoV-2-PP

实验名称：qHTS for inhibitors of Vif-A3G interactions: Validation 来源：NCGC 靶标：DNA dC->dU-editing enzyme APOBEC-3G [Homo sapiens] External Id：VIFG001

实验名称：Primary Screen Inhibitors of CD40 Signaling in BL2 Cells Measured in Cell-Based Syste... 来源：Broad Institute 靶标：N/A External Id：7124-01_Inhibitor_SinglePoint_HTS_Activity

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CI-966英文别名

• 1-[2-[bis[4-(trifluoromethyl)phenyl]methoxy]ethyl]-1,2,5,6-tetrahydro-3-pyridine carboxylic acid
• 1-(2-(Bis(4-(trifluoromethyl)phenyl)methoxy)ethyl)-1,2,5,6-tetrahydropyridine-3-carboxylic acid
• CI-966
• 1,2,5,6-tetrahydro-1-<2-<bis<4-(trifluoromethyl)phenyl>methoxy>ethyl>-3-pyridinecarboxylic acid
• 3-Pyridinecarboxylicacid,1-[2-[bis[4-(trifluoromethyl)phenyl]methoxy]ethyl]-1,2,5,6-tetrahydro
• Tocris-1296