4-Hydroxytoremifene

• 常用名: 4-Hydroxytoremifene
• 英文名: 4-Hydroxytoremifene
• CAS号: 110503-62-3
• 分子量: 421.95900
• 密度: 1.152g/cm3
• 沸点: 567.7ºC at 760mmHg
• 分子式: C₂₆H₂₈ClNO₂
• 熔点: N/A
• 闪点: 297.2ºC

4-Hydroxytoremifene用途

4-Hydroxytoremifene is a selective estrogen receptor modulator toremifene active metabolite.

4-Hydroxytoremifene名称

• 英文名: 4-[(Z)-4-chloro-1-[4-[2-(dimethylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol

4-Hydroxytoremifene物理化学性质

• 密度: 1.152g/cm3
• 沸点: 567.7ºC at 760mmHg
• 分子式: C₂₆H₂₈ClNO₂
• 分子量: 421.95900
• 闪点: 297.2ºC
• 精确质量: 421.18100
• PSA: 32.70000
• LogP: 5.62190
• InChIKey: OIUCUUXSMIJSEB-QPLCGJKRSA-N
• SMILES: CN(C)CCOc1ccc(C(=C(CCCl)c2ccccc2)c2ccc(O)cc2)cc1
• 蒸汽压: 1.71E-13mmHg at 25°C
• 折射率: 1.602

4-Hydroxytoremifene靶点实验

查看更多实验

实验名称：Retention time of the compound 来源：ChEMBL 靶标：N/A External Id：CHEMBL3530268

实验名称：Displacement of [3H]4-OHT from ERRgamma 来源：ChEMBL 靶标：Estrogen-related receptor gamma External Id：CHEMBL867061

实验名称：Activity of human SULT1A1 expressed in escherichia coli assessed as enzyme-mediated 4... 来源：ChEMBL 靶标：Sulfotransferase 1A1 External Id：CHEMBL3540604

实验名称：Radioligand Displacement Assay from Article 10.1016/j.bmcl.2005.11.030: "Structure-gu... 来源：BindingDB 靶标：N/A External Id：BindingDB_2597_1

实验名称：Activity of human SULT1E1 expressed in escherichia coli assessed as enzyme-mediated 4... 来源：ChEMBL 靶标：Sulfotransferase 1E1 External Id：CHEMBL3540605

实验名称：Selectivity for ERRgamma over ERalpha relative to 4-hydroxytamoxifen 来源：ChEMBL 靶标：N/A External Id：CHEMBL865895

实验名称：Displacement of [3H]estradiol from ERalpha 来源：ChEMBL 靶标：Estrogen receptor External Id：CHEMBL867062

实验名称：Drug metabolism in human liver cytosol assessed as 4-(4-chloro-1-(4-(2-(dimethylamino... 来源：ChEMBL 靶标：Liver cytosol External Id：CHEMBL3540884

实验名称：Drug metabolism in human liver cytosol assessed as SULT1A1*1/2 single nucleotide poly... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3540885

实验名称：Drug metabolism in human liver cytosol assessed as 4-(4-chloro-1-(4-(2-(dimethylamino... 来源：ChEMBL 靶标：Liver cytosol External Id：CHEMBL3540882

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4-Hydroxytoremifene英文别名

• Z-4-chloro-1-(4-hydroxyphenyl)-1-[4-[2-(N,N-dimethylamino)ethoxy]phenyl]-2-phenyl-1-butene
• 4-HYDROXYTORMIFENE
• 4-Hydroxytoremifene
• (Z)-4-Hydroxytoremifene
• 4-hydroxytamoxifen (4-OHT) analog,3