P-2281

更新时间：2025-08-27 18:02:32

P-2281结构式	常用名	P-2281	英文名	P-2281
	CAS号	1112994-35-0	分子量	209.63
	密度	N/A	沸点	N/A
	分子式	C₉H₈ClN₃O	熔点	N/A
	MSDS	N/A	闪点	N/A

P-2281用途

P-2281是一种mTOR抑制剂,具有改善结肠炎的活性。

英文名	P-2281

描述	P-2281是一种mTOR抑制剂,具有改善结肠炎的活性。
参考文献	1. AbuRahma AF, Abu-Halimah S, Hass SM, Nanjundappa A, Stone PA, Mousa A, Lough E, Dean LS. Carotid artery stenting outcomes are equivalent to carotid endarterectomy outcomes for patients with post-carotid endarterectomy stenosis. J Vasc Surg. 2010 Nov;52(5):1180-7. doi: 10.1016/j.jvs.2010.06.074. Epub 2010 Aug 8. PubMed PMID: 20692794.

分子式	C₉H₈ClN₃O
分子量	209.63
InChIKey	VFOLQYOVUCHHET-UHFFFAOYSA-N
SMILES	CC(Cl)C(=O)Nc1ccc(C#N)nc1

实验名称：Stability in rat plasma
来源：ChEMBL
靶标：Plasma
External Id：CHEMBL973414

实验名称：Stability in mouse plasma
来源：ChEMBL
靶标：Plasma
External Id：CHEMBL973413

实验名称：Stability in human plasma
来源：ChEMBL
靶标：Plasma
External Id：CHEMBL973415

实验名称：Inhibition of mTOR in human H460 cells assessed as inhibition of FCS-induced phosphor...
来源：ChEMBL
靶标：Serine/threonine-protein kinase mTOR
External Id：CHEMBL973410

实验名称：Inhibition of mTOR in human H460 cells assessed as inhibition of FCS-induced phosphor...
来源：ChEMBL
靶标：Serine/threonine-protein kinase mTOR
External Id：CHEMBL973409

实验名称：Inhibition of concanavalin A-induced IFN-gamma production in human PBMC cells
来源：ChEMBL
靶标：PBMC
External Id：CHEMBL973412

实验名称：Inhibition of mTOR in human HCT116 cells assessed as inhibition of FCS-induced phosph...
来源：ChEMBL
靶标：Serine/threonine-protein kinase mTOR
External Id：CHEMBL973411

实验名称：Decrease in dextran sulfate sodium-induced edema in mouse at 150 mg/kg, ip administer...
来源：ChEMBL
靶标：Mus musculus
External Id：CHEMBL973422

实验名称：Reversal of dextran sulfate sodium-induced shortening of colon in mouse at 150 mg/kg,...
来源：ChEMBL
靶标：Mus musculus
External Id：CHEMBL973421

实验名称：Protection against dextran sulfate sodium-induced crypt damage in mouse at 150 mg/kg,...
来源：ChEMBL
靶标：Mus musculus
External Id：CHEMBL973424

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