7-chloro-6-fluoro-4-hydroxy-2-methylchroman-4-acetic acid

• 常用名: 7-chloro-6-fluoro-4-hydroxy-2-methylchroman-4-acetic acid
• 英文名: 7-chloro-6-fluoro-4-hydroxy-2-methylchroman-4-acetic acid
• CAS号: 111477-47-5
• 分子量: 274.67300
• 密度: 1.359g/cm3
• 沸点: 374.1ºC at 760mmHg
• 分子式: C₁₂H₁₂ClFO₄
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-[(2R,4R)-7-chloro-6-fluoro-4-hydroxy-2-methyl-2,3-dihydrochromen-4-yl]acetic acid

物理化学性质

• 密度: 1.359g/cm3
• 沸点: 374.1ºC at 760mmHg
• 分子式: C₁₂H₁₂ClFO₄
• 分子量: 274.67300
• 精确质量: 274.04100
• PSA: 66.76000
• LogP: 2.31240
• InChIKey: BRXHBAFNICPNFH-SREIQFSDSA-N
• SMILES: CC1CC(O)(CC(=O)O)c2cc(F)c(Cl)cc2O1
• 蒸汽压: 2.93E-06mmHg at 25°C
• 折射率: 1.528

靶点实验

查看更多实验

实验名称：ARI(aldose reductase inhibitor) enantiospecificity against human placental aldose red... 来源：ChEMBL 靶标：Aldo-keto reductase family 1 member B1 External Id：CHEMBL643111

实验名称：In vivo inhibition of sorbitol accumulation in sciatic nerves from streptozotocin-dia... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL785612

实验名称：Compound was tested in vitro for its inhibitory activity against human placental aldo... 来源：ChEMBL 靶标：Aldo-keto reductase family 1 member B1 External Id：CHEMBL641355

实验名称：In vivo inhibition of sorbitol accumulation in sciatic nerves from streptozotocin-dia... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL786126

实验名称：In vivo inhibition of sorbitol accumulation in sciatic nerves from streptozotocin-dia... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL785615

实验名称：In vivo inhibition of sorbitol accumulation in sciatic nerves from streptozotocin-dia... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL785616

实验名称：In vivo inhibition of sorbitol accumulation in sciatic nerves from streptozotocin-dia... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL785613

实验名称：In vivo inhibition of sorbitol accumulation in sciatic nerves from streptozotocin-dia... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL785614

实验名称：In vivo inhibition of sorbitol accumulation in sciatic nerves from streptozotocin-dia... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL785619

实验名称：Nerve concentration at 3h after the last dose of 25 mg/kg for 5 days. 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL879374

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英文别名

• 7-Chloro-6-fluoro-c-4-hydroxy-r-2-methylchroman-4-acetic Acid
• 7-Chloro-6-fluoro-4-hydroxy-2-methylchroman-4-acetic acid
• 7-Cl-6-F-Hmca
• 2R,4R-7-chloro-6-fluoro-4-hydroxy-2-methylchroman-4-acetic acid
• UNII-7BB546DQ6H