guanidine

• 常用名: guanidine
• 英文名: guanidine
• CAS号: 113-00-8
• 分子量: 59.07050
• 密度: 1.55g/cm3
• 沸点: 132.9ºC at 760mmHg
• 分子式: CH₅N₃
• 熔点: N/A
• 闪点: 34.2ºC

guanidine用途

用作有机合成中间体。主要用于制造磺胺药物和染料。因为游离胍难于分离，所以一般商品是其盐类，如盐酸胍、硝酸胍、碳酸胍、硫酸胍等。

guanidine名称

• 英文名: guanidine

guanidine物理化学性质

• 密度: 1.55g/cm3
• 沸点: 132.9ºC at 760mmHg
• 分子式: CH₅N₃
• 分子量: 59.07050
• 闪点: 34.2ºC
• 精确质量: 59.04830
• PSA: 75.89000
• LogP: 0.33890
• InChIKey: ZRALSGWEFCBTJO-UHFFFAOYSA-N
• SMILES: N=C(N)N
• 蒸汽压: 8.67mmHg at 25°C
• 折射率: 1.595
• 计算化学:

  1.疏水参数计算参考值（XlogP）:-1.3

  2.氢键供体数量:3

  3.氢键受体数量:1

  4.可旋转化学键数量:0

  5.互变异构体数量:无

  6.拓扑分子极性表面积75.9

  7.重原子数量:4

  8.表面电荷:0

  9.复杂度:26.3

  10.同位素原子数量:0

  11.确定原子立构中心数量:0

  12.不确定原子立构中心数量:0

  13.确定化学键立构中心数量:0

  14.不确定化学键立构中心数量:0

  15.共价键单元数量:1

• 更多:

  1.性状：无色结晶

  2. 熔点（ºC）：50

  3.溶解性：极易溶于水及醇。有潮解性，易从空气中吸收二氧化碳，呈强碱性。加热至160℃时分解为三聚氰胺及氨。

guanidine毒性和生态

guanidine安全信息

• 危险品运输编码: UN 1759
• 包装等级: II

guanidine制备

由氰氨化钙与碘化铵作用或尿素与氨在加压下反应制得

guanidine靶点实验

查看更多实验

实验名称：TP_TRANSPORTER: uptake in Xenopus laevis oocytes 来源：ChEMBL 靶标：Solute carrier family 22 member 3 External Id：CHEMBL2076472

实验名称：TP_TRANSPORTER: inhibition of TEA uptake (TEA: 5 uM, Guanidine: 1000 uM) in OCT2-expr... 来源：ChEMBL 靶标：Solute carrier family 22 member 2 External Id：CHEMBL2077800

实验名称：The chemical genetic matrix (CGM) dataset as reported in Wildenhain et al. (2015) Pre... 来源：11924 靶标：N/A External Id：CGM data for Cell Systems paper Dec 2015

实验名称：TP_TRANSPORTER: inhibition of TEA uptake (TEA: 5 uM, Guanidine: 1000 uM) in OCT2A-exp... 来源：ChEMBL 靶标：Solute carrier family 22 member 2 External Id：CHEMBL2077799

实验名称：Selectivity index, ratio of CC50 for human RD cells to EC50 for Enterovirus D68 US/KY... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4388280

实验名称：Antirhinovirus activity against rhinovirus serotype 14 which were grown on Ohio HeLa ... 来源：ChEMBL 靶标：Human rhinovirus sp. External Id：CHEMBL857959

实验名称：Antiviral activity against the Coxsackie B5 virus (RNA virus) at a concentration of 3... 来源：ChEMBL 靶标：Coxsackievirus B5 External Id：CHEMBL666395

实验名称：Antirhinovirus activity against rhinovirus serotype 39 which were grown on Ohio HeLa ... 来源：ChEMBL 靶标：Human rhinovirus sp. External Id：CHEMBL801286

实验名称：Antirhinovirus activity against rhinovirus serotype 29 which were grown on Ohio HeLa ... 来源：ChEMBL 靶标：Human rhinovirus sp. External Id：CHEMBL799323

实验名称：TP_TRANSPORTER: inhibition of TEA uptake (TEA: 20 uM, Guanidine: 5000 uM) in OCTN2-ex... 来源：ChEMBL 靶标：Solute carrier family 22 member 5 External Id：CHEMBL2078078

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guanidine英文别名

• Imidourea
• amino-amidine
• Aminoformamidine
• Carbamidine
• Iminourea
• EINECS 204-021-8
• guanidino acid
• Guanidin
• Aminomethanamidine
• Carbamamidine