1-cyclopropyl-6-fluoro-7-[3-(methylaminomethyl)pyrrolidin-1-yl]-4-oxo-1,8-naphthyridine-3-carboxylic acid

• 常用名: 1-cyclopropyl-6-fluoro-7-[3-(methylaminomethyl)pyrrolidin-1-yl]-4-oxo-1,8-naphthyridine-3-carboxylic acid
• 英文名: 1-cyclopropyl-6-fluoro-7-[3-(methylaminomethyl)pyrrolidin-1-yl]-4-oxo-1,8-naphthyridine-3-carboxylic acid
• CAS号: 113533-65-6
• 分子量: 360.38300
• 密度: 1.426g/cm3
• 沸点: 581.8ºC at 760 mmHg
• 分子式: C₁₈H₂₁FN₄O₃
• 熔点: N/A
• 闪点: 305.7ºC

名称

• 英文名: 1-cyclopropyl-6-fluoro-7-[3-(methylaminomethyl)pyrrolidin-1-yl]-4-oxo-1,8-naphthyridine-3-carboxylic acid

物理化学性质

• 密度: 1.426g/cm3
• 沸点: 581.8ºC at 760 mmHg
• 分子式: C₁₈H₂₁FN₄O₃
• 分子量: 360.38300
• 闪点: 305.7ºC
• 精确质量: 360.16000
• PSA: 87.46000
• LogP: 2.07030
• InChIKey: YIDARVDQIDLREN-UHFFFAOYSA-N
• SMILES: CNCC1CCN(c2nc3c(cc2F)c(=O)c(C(=O)O)cn3C2CC2)C1
• 蒸汽压: 2.23E-14mmHg at 25°C
• 折射率: 1.639

靶点实验

查看更多实验

实验名称：Minimum inhibitory concentration was evaluated in vitro against Staphylococcus aureus... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL808009

实验名称：Minimum inhibitory concentration against Escherichia coli 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL679318

实验名称：Minimum inhibitory concentration was evaluated in vitro against Staphylococcus aureus... 来源：ChEMBL 靶标：Staphylococcus aureus External Id：CHEMBL808008

实验名称：Minimum inhibitory concentration against Streptococcus pyogenes C203 in vitro. 来源：ChEMBL 靶标：Bacteria External Id：CHEMBL813960

实验名称：Antibacterial activity against Escherichia coli Vogel after subcutaneous administrati... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL676284

实验名称：Antibacterial activity against Escherichia coli Vogel after oral administration in mo... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL676283

实验名称：Antibacterial activity measured as mouse protection against Streptococcus pyogenes C ... 来源：ChEMBL 靶标：Streptococcus pyogenes External Id：CHEMBL809396

实验名称：Minimum inhibitory concentration was evaluated in vitro against Pseudomonas aeruginos... 来源：ChEMBL 靶标：Pseudomonas aeruginosa External Id：CHEMBL770146

实验名称：Compounds were evaluated in vivo for antibacterial activity for mouse protection agai... 来源：ChEMBL 靶标：Streptococcus pyogenes External Id：CHEMBL812034

实验名称：In vivo potency against Escherichia coli vogel using mouse protection assay when give... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL721985

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英文别名

• 1-cyclopropyl-6-fluoro-1,4-dihydro-7-<3-<(methylamino)methyl>-1-pyrrolidinyl>-4-oxo-1,8-naphthyridine-3-carboxylic acid
• 3-Quinolinecarboxylicacid,1-cyclopropyl-6-fluoro-1,4-dihydro-7-(8-methyl-3,8-diazabicyclo[3.2.1]oct-3-yl)-4-oxo
• 8,-naphthyridine-3-carboxylic acid
• 1-cyclopropyl-6-fluoro-1,4-dihydro-7-[3-[(methylamino)methyl]-1-pyrrolidinyl]-4-oxo-1
• 1-cyclopropyl-6-fluoro-1,4-dihydro-7-(8-methyl-3,8-diazabicyclo[3.2.1]oct-3-yl)-4-oxo-3-quinoline carboxylic acid
• CP-74,667