Philanthotoxin 343

更新时间：2026-07-01 21:16:21

Philanthotoxin 343结构式	常用名	Philanthotoxin 343	英文名	Philanthotoxin 343
	CAS号	115976-93-7	分子量	435.60300
	密度	N/A	沸点	N/A
	分子式	C₂₃H₄₁N₅O₃	熔点	N/A
	MSDS	美版	闪点	N/A

英文名	Philanthotoxin 343
英文别名	更多

分子式	C₂₃H₄₁N₅O₃
分子量	435.60300
精确质量	435.32100
PSA	128.51000
LogP	3.29800
InChIKey	DTWANULJDRVTFI-NRFANRHFSA-N
SMILES	CCCC(=O)NC(Cc1ccc(O)cc1)C(=O)NCCCNCCCCNCCCN

个人防护装备	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
危险品运输编码	NONH for all modes of transport

Open-channel blockade is less effective on GluN3B than GluN3A subunit-containing NMDA receptors

Eur. J. Pharmacol. 686(1-3) , 22-31, (2012)

The GluN3 subunits of the N-methyl-d-aspartate (NMDA) receptor are known to reduce its Ca2+ permeability and Mg2+ sensitivity, however, little is known about their effects on other channel blockers. c...

Neuroactive polyamine wasp toxins: nuclear magnetic resonance spectroscopic analysis of the protolytic properties of philanthotoxin-343.

J. Med. Chem. 39(2) , 515-21, (1996)

Acid-base properties (pKa values and proton distribution patterns) of philanthotoxin-343(PhTX-343) were investigated by 1H and 13C NMR titration. Chemical shift data and the total ionization shifts we...

A sequential high-yielding large-scale solution-method for synthesis of philanthotoxin analogues.

Eur. J. Med. Chem. 38(1) , 117-22, (2003)

A general, improved procedure for rapid synthesis of philanthotoxin analogues, a pharmacologically important class of polyamine conjugates, is described. The solution-phase procedure is illustrated by...

实验名称：Selectivity ratio of IC50 for rat recombinant GluA1A2 receptor flop isoform to IC50 f...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL1108950

实验名称：Antagonist activity at GluR1 expressed in Xenopus laevis oocytes assessed as inhibiti...
来源：ChEMBL
靶标：Metabotropic glutamate receptor 1
External Id：CHEMBL1274346

实验名称：Compound was evaluated for inhibitory activity against human embryonic muscle type Ni...
来源：ChEMBL
靶标：Acetylcholine receptor subunit delta
External Id：CHEMBL750563

实验名称：Antagonist activity at NR1-1a/NR2A receptor expressed in Xenopus laevis oocytes asses...
来源：ChEMBL
靶标：Glutamate receptor ionotropic, NMDA 2A
External Id：CHEMBL1274347

实验名称：Selectivity ratio of IC50 for NR1-1a/NR2A receptor to IC50 for GluR1
来源：ChEMBL
靶标：N/A
External Id：CHEMBL1274348

实验名称：Antagonist activity at GluR1 expressed in Xenopus laevis oocytes assessed as inhibiti...
来源：ChEMBL
靶标：Metabotropic glutamate receptor 1
External Id：CHEMBL1274349

实验名称：Inhibition of quisqualate-sensitive glutamate receptor in Schistocerca gregaria (dese...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL3049785

实验名称：Antagonist activity at GluR1 expressed in Xenopus laevis oocytes assessed as inhibiti...
来源：ChEMBL
靶标：Metabotropic glutamate receptor 1
External Id：CHEMBL1274350

实验名称：Antagonist activity at NR1-1a/NR2A receptor expressed in Xenopus laevis oocytes asses...
来源：ChEMBL
靶标：Glutamate receptor ionotropic, NMDA 2A
External Id：CHEMBL1274351

实验名称：Antagonist activity at NR1-1a/NR2A receptor expressed in Xenopus laevis oocytes asses...
来源：ChEMBL
靶标：Glutamate receptor ionotropic, NMDA 2A
External Id：CHEMBL1274352

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PhTX-343

philanthotoxin-343

philanthotoxin 343

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Philanthotoxin 343

Philanthotoxin 343名称

Philanthotoxin 343物理化学性质

Philanthotoxin 343安全信息

Philanthotoxin 343文献28

Philanthotoxin 343靶点实验

Philanthotoxin 343英文别名

本网页内容来自不同专业数据源，如对内容有疑义，欢迎联系service1@chemsrc.com。