1-(3-(2-Hydroxyethyl)-5-(3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)phenyl)cyclopropanecarbonitrile

• 常用名: 1-(3-(2-Hydroxyethyl)-5-(3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)phenyl)cyclopropanecarbonitrile
• 英文名: 1-(3-(2-Hydroxyethyl)-5-(3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)phenyl)cyclopropanecarbonitrile
• CAS号: 1160501-79-0
• 分子量: 372.3
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₁₅F₃N₄O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 1-(3-(2-Hydroxyethyl)-5-(3-(trifluoromethyl)-1H-pyrazolo[3,4-b]pyridin-4-yl)phenyl)cyclopropanecarbonitrile

物理化学性质

• 分子式: C₁₉H₁₅F₃N₄O
• 分子量: 372.3
• InChIKey: MTGNUTFABAEBRU-UHFFFAOYSA-N
• SMILES: N#CC1(c2cc(CCO)cc(-c3ccnc4n[nH]c(C(F)(F)F)c34)c2)CC1

靶点实验

查看更多实验

实验名称：Half life in beagle dog at 10 mg/kg, iv bolus dose 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL3368202

实验名称：Apparent oral clearance in beagle dog at 10 mg/kg, iv bolus dose 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL3368200

实验名称：AUC in beagle dog at 10 mg/kg, iv bolus dose 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL3368201

实验名称：Metabolic stability in rat liver microsomes assessed as compound remaining at 1 uM af... 来源：ChEMBL 靶标：Liver microsome External Id：CHEMBL3368194

实验名称：Metabolic stability in rat liver S9 fraction (-NADPH/UDPGA) assessed as compound rema... 来源：ChEMBL 靶标：Liver External Id：CHEMBL3368195

实验名称：Inhibition of full-length recombinant PKCepsilon (unknown origin) using ERMRPRKRQGSVR... 来源：ChEMBL 靶标：Protein kinase C epsilon type External Id：CHEMBL3368193

实验名称：Clearance in Sprague-Dawley rat at 0.5 mg/kg, iv bolus dose 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3368196

实验名称：Half life in Sprague-Dawley rat at 0.5 mg/kg, iv bolus dose 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3368197

共8条，当前第1页，共1页

1