8-[(2-Fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-7-carboxamide

• 常用名: 8-[(2-Fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-7-carboxamide
• 英文名: 8-[(2-Fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-7-carboxamide
• CAS号: 1168102-45-1
• 分子量: 456.21
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₆H₁₄FIN₄O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 8-[(2-Fluoro-4-iodophenyl)amino]-N-(2-hydroxyethoxy)imidazo[1,5-a]pyridine-7-carboxamide

物理化学性质

• 分子式: C₁₆H₁₄FIN₄O₃
• 分子量: 456.21
• InChIKey: GERXWWPNRKXYSR-UHFFFAOYSA-N
• SMILES: O=C(NOCCO)c1ccn2cncc2c1Nc1ccc(I)cc1F

靶点实验

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实验名称：Hepatic clearance in rat liver microsomes 来源：ChEMBL 靶标：Liver microsome External Id：CHEMBL3377706

实验名称：Hepatic clearance in human liver microsomes 来源：ChEMBL 靶标：Liver microsome External Id：CHEMBL3377705

实验名称：Hepatic clearance in dog liver microsomes 来源：ChEMBL 靶标：Liver microsome External Id：CHEMBL3377708

实验名称：Hepatic clearance in mouse liver microsomes 来源：ChEMBL 靶标：Liver External Id：CHEMBL3377707

实验名称：Total clearance in rat at 1 mg/kg, iv or 5 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3377710

实验名称：Hepatic clearance in cynomolgus monkey liver microsomes 来源：ChEMBL 靶标：N/A External Id：CHEMBL3377709

实验名称：Volume of distribution at steady state in rat at 1 mg/kg, iv or 5 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3377712

实验名称：Half life in rat at 1 mg/kg, iv or 5 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3377711

实验名称：Oral bioavailability in rat at 5 mg/kg 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3377714

实验名称：Dose normalized AUC in rat at 5 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3377713

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