(S)-N-(4-(((2S,5R)-5-((R)-hydroxy(phenyl)methyl)pyrrolidin-2-yl)methyl)phenyl)-5-oxo-1,2,3,5-tetrahydroindolizine-3-carboxamide

• 常用名: (S)-N-(4-(((2S,5R)-5-((R)-hydroxy(phenyl)methyl)pyrrolidin-2-yl)methyl)phenyl)-5-oxo-1,2,3,5-tetrahydroindolizine-3-carboxamide
• 英文名: (S)-N-(4-(((2S,5R)-5-((R)-hydroxy(phenyl)methyl)pyrrolidin-2-yl)methyl)phenyl)-5-oxo-1,2,3,5-tetrahydroindolizine-3-carboxamide
• CAS号: 1190389-13-9
• 分子量: 443.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₇H₂₉N₃O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (S)-N-(4-(((2S,5R)-5-((R)-hydroxy(phenyl)methyl)pyrrolidin-2-yl)methyl)phenyl)-5-oxo-1,2,3,5-tetrahydroindolizine-3-carboxamide

物理化学性质

• 分子式: C₂₇H₂₉N₃O₃
• 分子量: 443.5
• InChIKey: OZXUSBILVIKYQB-GEMTWJNPSA-N
• SMILES: C1C[C@@H](N[C@@H]1CC2=CC=C(C=C2)NC(=O)[C@@H]3CCC4=CC=CC(=O)N34)[C@@H](C5=CC=CC=C5)O

靶点实验

查看更多实验

实验名称：Stability in rat plasma assessed as parent compound remaining at 24 hrs by LC-MS anal... 来源：ChEMBL 靶标：Plasma External Id：CHEMBL3768505

实验名称：Intrinsic clearance in rhesus monkey liver microsomes 来源：ChEMBL 靶标：N/A External Id：CHEMBL3768504

实验名称：Intrinsic clearance in human liver microsomes 来源：ChEMBL 靶标：Liver microsome External Id：CHEMBL3768503

实验名称：Intrinsic clearance in dog liver microsomes 来源：ChEMBL 靶标：Liver microsome External Id：CHEMBL3768502

实验名称：Agonist activity at human beta3 adrenergic receptor expressed in CHO cells assessed a... 来源：ChEMBL 靶标：Beta-3 adrenergic receptor External Id：CHEMBL3768477

实验名称：Selectivity ratio of IC50 for human SERT to EC50 for human adrenergic beta3 receptor 来源：ChEMBL 靶标：N/A External Id：CHEMBL3768717

实验名称：Stability in rhesus monkey plasma assessed as parent compound remaining at 24 hrs by ... 来源：ChEMBL 靶标：Plasma External Id：CHEMBL3768716

实验名称：Stability in dog plasma assessed as parent compound remaining at 24 hrs by LC-MS anal... 来源：ChEMBL 靶标：Plasma External Id：CHEMBL3768715

实验名称：Stability in human plasma assessed as parent compound remaining at 24 hrs by LC-MS an... 来源：ChEMBL 靶标：Plasma External Id：CHEMBL3768481

实验名称：Plasma clearance in dog at 0.5 mg/kg, iv or 2 mg/kg, po 来源：ChEMBL 靶标：Canis lupus familiaris External Id：CHEMBL3768480

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