4-{3-[2-Amino-5-(2-Methoxyethoxy)pyrimidin-4-Yl]-1h-Indol-5-Yl}-2-Methylbut-3-Yn-2-Ol

• 常用名: 4-{3-[2-Amino-5-(2-Methoxyethoxy)pyrimidin-4-Yl]-1h-Indol-5-Yl}-2-Methylbut-3-Yn-2-Ol
• 英文名: 4-{3-[2-Amino-5-(2-Methoxyethoxy)pyrimidin-4-Yl]-1h-Indol-5-Yl}-2-Methylbut-3-Yn-2-Ol
• CAS号: 1202763-91-4
• 分子量: 366.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₂₂N₄O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 4-{3-[2-Amino-5-(2-Methoxyethoxy)pyrimidin-4-Yl]-1h-Indol-5-Yl}-2-Methylbut-3-Yn-2-Ol

物理化学性质

• 分子式: C₂₀H₂₂N₄O₃
• 分子量: 366.4
• InChIKey: ZZIZLABGKZWVAW-UHFFFAOYSA-N
• SMILES: CC(C)(C#CC1=CC2=C(C=C1)NC=C2C3=NC(=NC=C3OCCOC)N)O

靶点实验

查看更多实验

实验名称：Cytotoxicity against human MDA-MB-231 cells assessed as cell viability at 1 uM after ... 来源：ChEMBL 靶标：MDA-MB-231 External Id：CHEMBL4259055

实验名称：Inhibition of NFkappaB activation in human MDA-MB-231 cells at 1 uM after 6 hrs by du... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4259049

实验名称：Inhibition of NFkappaB activation in human SKBR3 cells at 1 uM after 6 hrs by dual lu... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4259052

实验名称：Experimentally measured binding affinity data (IC50) for protein-ligand complexes der... 来源：Shanghai Institute of Organic Chemistry 靶标：N/A External Id：PDBbind-IC50 for protein-ligand complexes

实验名称：Inhibition of His6-tagged human NIK (330 to 680 residues) S549D mutant expressed in b... 来源：ChEMBL 靶标：Mitogen-activated protein kinase kinase kinase 14 External Id：CHEMBL5151674

实验名称：Cytotoxicity against human SKBR3 cells assessed as cell viability at 1 uM after 6 hrs... 来源：ChEMBL 靶标：SK-BR-3 External Id：CHEMBL4259063

实验名称：Cytotoxicity against human EJM cells assessed as cell viability at 1 uM after 6 hrs b... 来源：ChEMBL 靶标：EJM External Id：CHEMBL4259058

实验名称：Inhibition of NIK (unknown origin) autophosphorylation after 1 hr by chemiluminescent... 来源：ChEMBL 靶标：Mitogen-activated protein kinase kinase kinase 14 External Id：CHEMBL2346384

实验名称：Inhibition of NIK in human HT-29 cells assessed as LTalpha/beta2-induced p100 process... 来源：ChEMBL 靶标：Mitogen-activated protein kinase kinase kinase 14 External Id：CHEMBL2346383

实验名称：Inhibition of recombinant human full-length N-terminal GST-fused/His6-tagged IKKepsil... 来源：ChEMBL 靶标：Inhibitor of nuclear factor kappa-B kinase subunit epsilon External Id：CHEMBL4259040

共14条，当前第1页，共2页

1

2