Urea, N-ethyl-N'-[4-[5,6,7,8-tetrahydro-4-(4-morpholinyl)-7-(2-pyrimidinyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]

• 常用名: Urea, N-ethyl-N'-[4-[5,6,7,8-tetrahydro-4-(4-morpholinyl)-7-(2-pyrimidinyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]
• 英文名: Urea, N-ethyl-N'-[4-[5,6,7,8-tetrahydro-4-(4-morpholinyl)-7-(2-pyrimidinyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]
• CAS号: 1207358-29-9
• 分子量: 460.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₄H₂₈N₈O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: Urea, N-ethyl-N'-[4-[5,6,7,8-tetrahydro-4-(4-morpholinyl)-7-(2-pyrimidinyl)pyrido[3,4-d]pyrimidin-2-yl]phenyl]

物理化学性质

• 分子式: C₂₄H₂₈N₈O₂
• 分子量: 460.5
• InChIKey: GONDQBGXBXPIQL-UHFFFAOYSA-N
• SMILES: CCNC(=O)Nc1ccc(-c2nc3c(c(N4CCOCC4)n2)CCN(c2ncccn2)C3)cc1

靶点实验

查看更多实验

实验名称：Selectivity ratio of Ki for PI3Kdelta to Ki for mTOR 来源：ChEMBL 靶标：N/A External Id：CHEMBL2186392

实验名称：Selectivity ratio of Ki for PI3Kalpha to Ki for mTOR 来源：ChEMBL 靶标：N/A External Id：CHEMBL2186804

实验名称：Clearance in human liver microsomes 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL2186382

实验名称：Inhibition of recombinant mTOR (1360 to 2549)+GBL (unknown origin) using GFP-4E-BP1 a... 来源：ChEMBL 靶标：Serine/threonine-protein kinase mTOR External Id：CHEMBL2344477

实验名称：Inhibition of CYP2C19-mediated mephenytoin metabolism 来源：ChEMBL 靶标：Cytochrome P450 2C19 External Id：CHEMBL2186383

实验名称：Selectivity ratio of Ki for PI3K-alpha (unknown origin) to Ki for mTOR (unknown origi... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2344476

实验名称：Clearance in mouse liver microsomes 来源：ChEMBL 靶标：Liver External Id：CHEMBL2186380

实验名称：Antiproliferative activity against PTEN-null human PC3 cells 来源：ChEMBL 靶标：PC-3 External Id：CHEMBL2344475

实验名称：Clearance in rat liver microsomes 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL2186381

实验名称：Inhibition of CYP2D6-mediated dextromethorphan metabolism 来源：ChEMBL 靶标：Cytochrome P450 2D6 External Id：CHEMBL2186386

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