3-[5-(2-Chloro-phenyl)-7-trifluoromethyl-1H-benzimidazol-2-yl]-1-oxa-2-aza-spiro[4.5]dec-2-ene

• 常用名: 3-[5-(2-Chloro-phenyl)-7-trifluoromethyl-1H-benzimidazol-2-yl]-1-oxa-2-aza-spiro[4.5]dec-2-ene
• 英文名: 3-[5-(2-Chloro-phenyl)-7-trifluoromethyl-1H-benzimidazol-2-yl]-1-oxa-2-aza-spiro[4.5]dec-2-ene
• CAS号: 1221349-56-9
• 分子量: 433.9
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₂H₁₉ClF₃N₃O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 3-[5-(2-Chloro-phenyl)-7-trifluoromethyl-1H-benzimidazol-2-yl]-1-oxa-2-aza-spiro[4.5]dec-2-ene

物理化学性质

• 分子式: C₂₂H₁₉ClF₃N₃O
• 分子量: 433.9
• InChIKey: RFGUIBKXEBMLGQ-UHFFFAOYSA-N
• SMILES: FC(F)(F)c1cc(-c2ccccc2Cl)cc2[nH]c(C3=NOC4(CCCCC4)C3)nc12

靶点实验

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实验名称：Inhibition of icilin-induced WDS behavior in rat at 10 mg/kg, po after 120 mins 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1655530

实验名称：Antiallodynic activity against chronic constriction injury cold allodynia in Sprague-... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1655532

实验名称：Metabolic stability in human liver microsomes assessed as compound remaining after 10... 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL1655517

实验名称：Metabolic stability in rat liver microsomes assessed as compound remaining after 10 m... 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL1655518

实验名称：Metabolic stability in dog liver microsomes assessed as compound remaining after 10 m... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1655519

实验名称：Antagonist activity at canine TRPM8 expressed in HEK293 cells assessed as inhibition ... 来源：ChEMBL 靶标：Transient receptor potential M8 protein External Id：CHEMBL1656182

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