N-[5-(1-methylcyclopropyl)-1H-pyrazol-3-yl]-5-(5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yloxy)indole-1-carboxamide

• 常用名: N-[5-(1-methylcyclopropyl)-1H-pyrazol-3-yl]-5-(5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yloxy)indole-1-carboxamide
• 英文名: N-[5-(1-methylcyclopropyl)-1H-pyrazol-3-yl]-5-(5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yloxy)indole-1-carboxamide
• CAS号: 1229450-33-2
• 分子量: 429.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₂₃N₇O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-[5-(1-methylcyclopropyl)-1H-pyrazol-3-yl]-5-(5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yloxy)indole-1-carboxamide

物理化学性质

• 分子式: C₂₃H₂₃N₇O₂
• 分子量: 429.5
• InChIKey: CXHHBESKHSJGOL-UHFFFAOYSA-N
• SMILES: CC1(c2cc(NC(=O)n3ccc4cc(Oc5ncnc6c5CCNC6)ccc43)n[nH]2)CC1

靶点实验

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实验名称：Dose normalized AUC (0 to 24 hrs) in Brown Norway rat plasma at 6 mg/kg, po 来源：ChEMBL 靶标：Plasma External Id：CHEMBL3749268

实验名称：Antiangiogenic activity in po dosed Brown Norway rat laser-induced choroidal neovascu... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3749267

实验名称：Antiangiogenic activity in po dosed C57BL/6 mouse laser-induced choroidal neovascular... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3749266

实验名称：Inhibition of human ERG channel by automated Q-patch assay 来源：ChEMBL 靶标：Potassium voltage-gated channel subfamily H member 2 External Id：CHEMBL3749265

实验名称：Dose normalized AUC (0 to 24 hrs) in Brown Norway rat posteior eye cup at 6 mg/kg, po 来源：ChEMBL 靶标：N/A External Id：CHEMBL3749272

实验名称：Dose normalized AUC (0 to 24 hrs) in Brown Norway rat retina at 6 mg/kg, po 来源：ChEMBL 靶标：N/A External Id：CHEMBL3749270

实验名称：Dose normalized Cmax in Brown Norway rat retina at 6 mg/kg, po 来源：ChEMBL 靶标：N/A External Id：CHEMBL3749276

实验名称：Dose normalized Cmax in Brown Norway rat plasma at 6 mg/kg, po 来源：ChEMBL 靶标：Plasma External Id：CHEMBL3749274

实验名称：Dose normalized plasma concentration in Brown Norway rat plasma at 6 mg/kg, po measur... 来源：ChEMBL 靶标：Plasma External Id：CHEMBL3749590

实验名称：Dose normalized Cmax in Brown Norway rat posteior eye cup at 6 mg/kg, po 来源：ChEMBL 靶标：N/A External Id：CHEMBL3749588

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