5-amino-1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-quinoline-3-carb oxylic acid

• 常用名: 5-amino-1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-quinoline-3-carb oxylic acid
• 英文名: 5-amino-1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-yl-quinoline-3-carb oxylic acid
• CAS号: 123016-42-2
• 分子量: 346.35600
• 密度: 1.512g/cm3
• 沸点: 661.8ºC at 760mmHg
• 分子式: C₁₇H₁₉FN₄O₃
• 熔点: N/A
• 闪点: 354.1ºC

名称

• 英文名: 5-amino-1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid

物理化学性质

• 密度: 1.512g/cm3
• 沸点: 661.8ºC at 760mmHg
• 分子式: C₁₇H₁₉FN₄O₃
• 分子量: 346.35600
• 闪点: 354.1ºC
• 精确质量: 346.14400
• PSA: 100.59000
• LogP: 2.14050
• InChIKey: YDCDVKGBYXKGGH-UHFFFAOYSA-N
• SMILES: Nc1c(F)c(N2CCNCC2)cc2c1c(=O)c(C(=O)O)cn2C1CC1
• 蒸汽压: 2.03E-18mmHg at 25°C
• 折射率: 1.689

靶点实验

查看更多实验

实验名称：MIC ratio measured as the mean MICs of gram-negative bacteria 来源：ChEMBL 靶标：N/A External Id：CHEMBL682678

实验名称：Antibacterial activity was determined against gram positive organism, Streptococcus p... 来源：ChEMBL 靶标：Streptococcus pneumoniae External Id：CHEMBL799746

实验名称：Antibacterial activity was determined against gram positive organism, Streptococcus f... 来源：ChEMBL 靶标：Enterococcus faecalis External Id：CHEMBL799853

实验名称：Minimum inhibitory concentration against Escherichia coli DNA-gyrase in supercoiling ... 来源：ChEMBL 靶标：DNA gyrase subunit B External Id：CHEMBL664852

实验名称：Antibacterial activity was determined against gram negative organism, Providencia ret... 来源：ChEMBL 靶标：Bacteria External Id：CHEMBL755847

实验名称：Antibacterial activity was determined against gram negative organism, Pseudomonas aer... 来源：ChEMBL 靶标：Pseudomonas aeruginosa External Id：CHEMBL754839

实验名称：Antibacterial activity was determined against gram positive organism, Streptococcus p... 来源：ChEMBL 靶标：Streptococcus pyogenes External Id：CHEMBL801925

实验名称：MIC ratio measured as the mean MICs of gram-positive bacteria 来源：ChEMBL 靶标：Bacteria External Id：CHEMBL682689

实验名称：Antibacterial activity was determined against gram negative organism, Klebsiella pneu... 来源：ChEMBL 靶标：Klebsiella pneumoniae External Id：CHEMBL702642

实验名称：The in vivo potency was determined in female charles river CD-1 mice infected with Es... 来源：ChEMBL 靶标：Escherichia coli External Id：CHEMBL674838

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英文别名

• 5-amino-1-cyclopropyl-6-fluoro-7-(1-piperazinyl)-1,4-dihydro-4-oxoquinoline-3-carboxylic acid
• 3-Quinolinecarboxylicacid,5-amino-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-(1-piperazinyl)
• 3-Quinolinecarboxylic acid,1,4-dihydro-5-amino-1-cyclopropyl-6-fluoro-4-oxo-7-(1-piperazinyl)
• 5-amino-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazinylquinoline-3-carboxylic acid