4-{4-[1-(Methylsulfonyl)cyclopropyl]-6-morpholin-4-ylpyrimidin-2-yl}-1H-indole

• 常用名: 4-{4-[1-(Methylsulfonyl)cyclopropyl]-6-morpholin-4-ylpyrimidin-2-yl}-1H-indole
• 英文名: 4-{4-[1-(Methylsulfonyl)cyclopropyl]-6-morpholin-4-ylpyrimidin-2-yl}-1H-indole
• CAS号: 1233338-73-2
• 分子量: 398.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₂₂N₄O₃S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 4-{4-[1-(Methylsulfonyl)cyclopropyl]-6-morpholin-4-ylpyrimidin-2-yl}-1H-indole

物理化学性质

• 分子式: C₂₀H₂₂N₄O₃S
• 分子量: 398.5
• InChIKey: UUEAFRKZMCDHFV-UHFFFAOYSA-N
• SMILES: CS(=O)(=O)C1(c2cc(N3CCOCC3)nc(-c3cccc4[nH]ccc34)n2)CC1

靶点实验

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实验名称：Bioavailability in rat 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2330575

实验名称：Fraction unbound in rat plasma 来源：ChEMBL 靶标：Plasma External Id：CHEMBL2330573

实验名称：AUC in Han-Wistar rat at 4 umol/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2330579

实验名称：Octanol-phosphate buffer partition co-efficient, log D of the compound at 10 uM at pH... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4269679

实验名称：Volume of distribution in rat 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2330578

实验名称：Inhibition of ATR in human HT29 cells after 60 mins by Hoechst 33258 staining-based a... 来源：ChEMBL 靶标：Serine/threonine-protein kinase ATR External Id：CHEMBL4269678

实验名称：Plasma clearance in rat 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2330577

实验名称：Time dependent inhibition of CYP3A4 in human liver microsomes at 10 uM using midazola... 来源：ChEMBL 靶标：Cytochrome P450 3A4 External Id：CHEMBL4269680

实验名称：ASTRAZENECA: Octan-1-ol/water (pH7.4) distribution coefficent measured by a shake fl... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301363

实验名称：Inhibition of CYP2C19 in human liver microsomes using midazolam as substrate preincub... 来源：ChEMBL 靶标：Cytochrome P450 2C19 External Id：CHEMBL4269687

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