P7C3-A20

• 常用名: P7C3-A20
• 英文名: P7C3-A20
• CAS号: 1235481-90-9
• 分子量: 506.206
• 密度: 1.6±0.1 g/cm3
• 沸点: 641.3±55.0 °C at 760 mmHg
• 分子式: C₂₂H₁₉Br₂FN₂O
• 熔点: N/A
• 闪点: 341.7±31.5 °C

P7C3-A20用途

P7C3-A20是P7C3的衍生物,具有强效的神经保护活性。

P7C3-A20名称

• 中文名: 3,6-二溴-beta-氟-N-(3-甲氧基苯基)-9H-咔唑-9-丙胺
• 英文名: p7c3-a20

P7C3-A20生物活性

• 描述: P7C3-A20是P7C3的衍生物,具有强效的神经保护活性。
• 相关类别:
  信号通路 >> 其他 >> 其他
  研究领域 >> 神经疾病
• 参考文献:

  [1]. Blaya MO et al. Neuroprotective efficacy of a proneurogenic compound after traumatic brain injury.J Neurotrauma. 2014 Mar 1;31(5):476-86.

  [2]. Walker AK et al. The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasinghippocampal neurogenesis. Mol Psychiatry. 2015 Apr;20(4):500-8.

P7C3-A20物理化学性质

• 密度: 1.6±0.1 g/cm3
• 沸点: 641.3±55.0 °C at 760 mmHg
• 分子式: C₂₂H₁₉Br₂FN₂O
• 分子量: 506.206
• 闪点: 341.7±31.5 °C
• 精确质量: 503.984802
• PSA: 26.19000
• LogP: 6.96
• InChIKey: XNLTWMQBJFWQOU-UHFFFAOYSA-N
• SMILES: COc1cccc(NCC(F)Cn2c3ccc(Br)cc3c3cc(Br)ccc32)c1
• 外观性状: light yellow solid
• 蒸汽压: 0.0±1.9 mmHg at 25°C
• 折射率: 1.647
• 储存条件: -20℃

P7C3-A20靶点实验

查看更多实验

实验名称：Primary qHTS assay for small molecule inhibitors of Inositol hexaphosphate kinase 1 (... 来源：NCGC External Id：IP6K1-p1

实验名称：Cytotoxicity against Sprague-Dawley rat embryo cortex NSC assessed as cell viability ... 来源：ChEMBL 靶标：NSC External Id：CHEMBL2444919

实验名称：Cytotoxicity against Sprague-Dawley rat embryo cortex NSC assessed as shrinkage and r... 来源：ChEMBL 靶标：NSC External Id：CHEMBL2444918

实验名称：Cytochrome P450 family 3 subfamily A member 4 (CYP3A4) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A4437

实验名称：Cytochrome P450 family 2 subfamily D member 6 (CYP2D6) small molecule antagonists: lu... 来源：NCGC External Id：CYP2D6395

实验名称：Cytochrome P450 family 2 subfamily C member 9 (CYP2C9) small molecule antagonists: lu... 来源：NCGC External Id：CYP2C9536

实验名称：Neuroprotective activity against Sprague-Dawley rat embryo cortex NSC assessed as red... 来源：ChEMBL 靶标：NSC External Id：CHEMBL2444917

实验名称：Neuroprotective activity against Sprague-Dawley rat embryo cortex NSC assessed as red... 来源：ChEMBL 靶标：NSC External Id：CHEMBL2444915

实验名称：Neuroprotective activity against Sprague-Dawley rat embryo cortex NSC assessed as red... 来源：ChEMBL 靶标：NSC External Id：CHEMBL2444914

实验名称：Cytochrome P450 family 3 subfamily A member 7 (CYP3A7) small molecule antagonists: lu... 来源：NCGC External Id：CYP3A7681

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P7C3-A20英文别名

• N-[3-(3,6-Dibromo-9H-carbazol-9-yl)-2-fluoropropyl]-3-methoxyaniline
• N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-3-methoxyaniline
• P7C3A20