3-(1-{[3-Chloro-6-(3-furanyl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]carbonyl}-4-piperidinyl)-1,3-oxazolidine-2,4-dione

• 常用名: 3-(1-{[3-Chloro-6-(3-furanyl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]carbonyl}-4-piperidinyl)-1,3-oxazolidine-2,4-dione
• 英文名: 3-(1-{[3-Chloro-6-(3-furanyl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]carbonyl}-4-piperidinyl)-1,3-oxazolidine-2,4-dione
• CAS号: 1237840-80-0
• 分子量: 496.8
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₁₆ClF₃N₄O₅
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 3-(1-{[3-Chloro-6-(3-furanyl)-8-(trifluoromethyl)imidazo[1,2-a]pyridin-2-yl]carbonyl}-4-piperidinyl)-1,3-oxazolidine-2,4-dione

物理化学性质

• 分子式: C₂₁H₁₆ClF₃N₄O₅
• 分子量: 496.8
• InChIKey: WQBUZKJXZGSEIS-UHFFFAOYSA-N
• SMILES: O=C(c1nc2c(C(F)(F)F)cc(-c3ccoc3)cn2c1Cl)N1CCC(N2C(=O)COC2=O)CC1

靶点实验

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实验名称：AUC (0 to 24 hrs) in Sprague-Dawley rat at 5 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2173129

实验名称：Displacement of [3H]-3-(1-(3-chloro-6-isopropyl-8-(trifluoromethyl)imidazo[1,2-a]pyri... 来源：ChEMBL 靶标：Hepacivirus hominis External Id：CHEMBL2173189

实验名称：Antiviral activity against wild type HCV genotype 1a infected in human HuH7 cells aft... 来源：ChEMBL 靶标：Hepacivirus hominis External Id：CHEMBL2173142

实验名称：Antiviral activity against wild type HCV genotype 1b infected in human HuH7 cells aft... 来源：ChEMBL 靶标：Hepacivirus hominis External Id：CHEMBL2173187

实验名称：Clearance in Sprague-Dawley rat at 1 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2173132

实验名称：Volume of distribution at steady state in Sprague-Dawley rat at 1 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2173133

实验名称：Oral bioavailability in Sprague-Dawley rat at 5 mg/kg 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2173130

实验名称：Half life in Sprague-Dawley rat at 5 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2173131

实验名称：Solubility of the compound 来源：ChEMBL 靶标：N/A External Id：CHEMBL2173134

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