1-(6-methylpyridin-2-yl)-3-(6-oxo-2,3,4,10b-tetrahydro-1H-pyrido[2,1-a]isoindol-10-yl)urea

• 常用名: 1-(6-methylpyridin-2-yl)-3-(6-oxo-2,3,4,10b-tetrahydro-1H-pyrido[2,1-a]isoindol-10-yl)urea
• 英文名: 1-(6-methylpyridin-2-yl)-3-(6-oxo-2,3,4,10b-tetrahydro-1H-pyrido[2,1-a]isoindol-10-yl)urea
• CAS号: 1245654-67-4
• 分子量: 336.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₉H₂₀N₄O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 1-(6-methylpyridin-2-yl)-3-(6-oxo-2,3,4,10b-tetrahydro-1H-pyrido[2,1-a]isoindol-10-yl)urea

物理化学性质

• 分子式: C₁₉H₂₀N₄O₂
• 分子量: 336.4
• InChIKey: PWWHQERJKXLERO-UHFFFAOYSA-N
• SMILES: Cc1cccc(NC(=O)Nc2cccc3c2C2CCCCN2C3=O)n1

靶点实验

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实验名称：Inhibition of GST fused human recombinant DYRK1A expressed in Escherichia coli using ... 来源：ChEMBL 靶标：Dual specificity tyrosine-phosphorylation-regulated kinase 1A External Id：CHEMBL3787887

实验名称：Inhibition of human recombinant CDK5/p25 using histone H1 as substrate 来源：ChEMBL 靶标：Cyclin-dependent kinase 5 External Id：CHEMBL3787886

实验名称：Antiproliferative activity against human Caco2 cells after 48 hrs by Hoechst 3342 sta... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3787891

实验名称：Antiproliferative activity against human HuH7 cells after 48 hrs by Hoechst 3342 stai... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3787890

实验名称：Selectivity ratio of IC50 for human recombinant CDK5/p25 to IC50 for pig brain GSK3al... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3787889

实验名称：Inhibition of pig brain GSK3alpha/GSK3beta using GS-1 as substrate 来源：ChEMBL 靶标：Glycogen synthase kinase-3 beta External Id：CHEMBL3787888

实验名称：Antiproliferative activity against human NCI-H727 cells after 48 hrs by Hoechst 3342 ... 来源：ChEMBL 靶标：NCI-H727 External Id：CHEMBL3787895

实验名称：Antiproliferative activity against human PC3 cells after 48 hrs by Hoechst 3342 stain... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3787894

实验名称：Antiproliferative activity against human HCT116 cells after 48 hrs by Hoechst 3342 st... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3787893

实验名称：Antiproliferative activity against human MDA-MB-231 cells after 48 hrs by Hoechst 334... 来源：ChEMBL 靶标：MDA-MB-231 External Id：CHEMBL3787892

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