(E)-1-(2,5-dimethoxyphenyl)-3-[4-(dimethylamino)phenyl]-2-methylprop-2-en-1-one

• 常用名: (E)-1-(2,5-dimethoxyphenyl)-3-[4-(dimethylamino)phenyl]-2-methylprop-2-en-1-one
• 英文名: (E)-1-(2,5-dimethoxyphenyl)-3-[4-(dimethylamino)phenyl]-2-methylprop-2-en-1-one
• CAS号: 124711-23-5
• 分子量: 325.40200
• 密度: 1.113g/cm3
• 沸点: 496.8ºC at 760mmHg
• 分子式: C₂₀H₂₃NO₃
• 熔点: N/A
• 闪点: 254.2ºC

名称

• 英文名: (E)-1-(2,5-dimethoxyphenyl)-3-[4-(dimethylamino)phenyl]-2-methylprop-2-en-1-one

物理化学性质

• 密度: 1.113g/cm3
• 沸点: 496.8ºC at 760mmHg
• 分子式: C₂₀H₂₃NO₃
• 分子量: 325.40200
• 闪点: 254.2ºC
• 精确质量: 325.16800
• PSA: 38.77000
• LogP: 4.05600
• InChIKey: AJMWJDGKNKNYEW-WYMLVPIESA-N
• SMILES: COc1ccc(OC)c(C(=O)C(C)=Cc2ccc(N(C)C)cc2)c1
• 蒸汽压: 5.24E-10mmHg at 25°C
• 折射率: 1.594

靶点实验

查看更多实验

实验名称：Compound was evaluated for cytotoxic activity against K562 human chronic myelogenous ... 来源：ChEMBL 靶标：K562 External Id：CHEMBL701563

实验名称：Antiproliferative activity against human K562 cells after 5 days by MTT assay 来源：ChEMBL 靶标：K562 External Id：CHEMBL1039834

实验名称：Cell cycle arrest in human K562 cells assessed as accumulation at G0/G1 phase at 20 n... 来源：ChEMBL 靶标：K562 External Id：CHEMBL1046047

实验名称：Concentration required for 50% inhibition of tubulin polymerization 来源：ChEMBL 靶标：Tubulin beta-1 chain External Id：CHEMBL832453

实验名称：Binding affinity to tubulin in african green monkey Vero cells assessed as aberration... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1046052

实验名称：Inhibition of tubulin assembly by Woods method 来源：ChEMBL 靶标：N/A External Id：CHEMBL1046050

实验名称：Inhibition of cytoplasmic microtubule network assembly in rat-kangaroo PtK2 cells ass... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4002304

实验名称：In vitro antimitotic activity against HeLa cells after 1 hr exposure to the compound 来源：ChEMBL 靶标：HeLa External Id：CHEMBL690212

实验名称：Displacement of [3H]colchicine from tubulin assessed as bound colchicine at 0.05 to 1... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1046051

实验名称：Inhibition of cytoplasmic microtubule network assembly in rat-kangaroo PtK2 cells ass... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4002303

共20条，当前第1页，共2页

1

2

英文别名

• 1-(2,5-Dimethoxyphenyl)-3-(4-(dimethylamino)phenyl)-1-methyl-2-propen-1-one
• 1-(2,5-dimethoxyphenyl)-3-[4-(dimethylamino)phenyl]-2-methyl-2-propen-1-one
• 1-(2,5-dimethoxyphenyl)-3-[4-(dimethylamino)phenyl]-2-methylprop-2-en-1-one
• (E)-1-(2,5-dimethoxyphenyl)-3-(4-N,N-dimethylaminophenyl)-2-methylprop-2-en-1-one
• (E)-1-(2,5-dimethoxyphenyl)-3-[4-dimethylamino)phenyl]-2-methyl-2-propen-1-one
• 2-Propen-1-one,1-(2,5-dimethoxyphenyl)-3-(4-(dimethylamino)phenyl)-2-methyl-,(E)
• (E)-1-(2,5-dimethoxyphenyl)-3-(4-dimethylaminophenyl)-2-methylprop-2-en-1-one