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N-(3,5-dimethylphenyl)-6-(4-(trifluoromethoxy)phenyl)pyrazine-2-carboxamide

更新时间:2025-09-12 00:48:08

N-(3,5-dimethylphenyl)-6-(4-(trifluoromethoxy)phenyl)pyrazine-2-carboxamide结构式
N-(3,5-dimethylphenyl)-6-(4-(trifluoromethoxy)phenyl)pyrazine-2-carboxamide结构式
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常用名 N-(3,5-dimethylphenyl)-6-(4-(trifluoromethoxy)phenyl)pyrazine-2-carboxamide 英文名 N-(3,5-dimethylphenyl)-6-(4-(trifluoromethoxy)phenyl)pyrazine-2-carboxamide
CAS号 1258268-80-2 分子量 387.4
密度 N/A 沸点 N/A
分子式 C20H16F3N3O2 熔点 N/A
MSDS N/A 闪点 N/A

 名称

英文名 N-(3,5-dimethylphenyl)-6-(4-(trifluoromethoxy)phenyl)pyrazine-2-carboxamide

 物理化学性质

分子式 C20H16F3N3O2
分子量 387.4
InChIKey ZAXMOONEIUJTOM-UHFFFAOYSA-N
SMILES Cc1cc(C)cc(NC(=O)c2cncc(-c3ccc(OC(F)(F)F)cc3)n2)c1

 靶点实验

查看更多实验

实验名称:Inhibition of mouse NaV1.8 by electrophysiology
来源:ChEMBL
靶标:Sodium channel protein type 10 subunit alpha
External Id:CHEMBL1272887
实验名称:Inhibition of human NaV1.8 by electrophysiology
来源:ChEMBL
靶标:Sodium channel protein type 10 subunit alpha
External Id:CHEMBL1272888
实验名称:Selectivity ratio of IC50 for human NAv1.2 to IC50 for human Nav1.8
来源:ChEMBL
靶标:N/A
External Id:CHEMBL1272906
实验名称:Inhibition of tetrodotoxin-resistant NaV1.8 in rat DRG neuron by electrophysiology
来源:ChEMBL
靶标:Sodium channel protein type 10 subunit alpha
External Id:CHEMBL1272890
实验名称:Inhibition of human recombinant NaV1.2 at 3 uM by electrophysiology
来源:ChEMBL
靶标:Sodium channel protein type 2 subunit alpha
External Id:CHEMBL1286454
实验名称:Aqueous solubility of the compound
来源:ChEMBL
靶标:N/A
External Id:CHEMBL1286455
实验名称:Selectivity ratio of IC50 for human ERG to IC50 for human Nav1.8
来源:ChEMBL
靶标:N/A
External Id:CHEMBL1272909
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