3-(5-Amino-2-(2-methyl-4-(3-phosphonopropoxy)phenethyl)benzo[f][1,7]naphthyridin-8-yl)propanoic acid

• 常用名: 3-(5-Amino-2-(2-methyl-4-(3-phosphonopropoxy)phenethyl)benzo[f][1,7]naphthyridin-8-yl)propanoic acid
• 英文名: 3-(5-Amino-2-(2-methyl-4-(3-phosphonopropoxy)phenethyl)benzo[f][1,7]naphthyridin-8-yl)propanoic acid
• CAS号: 1258595-27-5
• 分子量: 523.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₇H₃₀N₃O₆P
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 3-(5-Amino-2-(2-methyl-4-(3-phosphonopropoxy)phenethyl)benzo[f][1,7]naphthyridin-8-yl)propanoic acid

物理化学性质

• 分子式: C₂₇H₃₀N₃O₆P
• 分子量: 523.5
• InChIKey: SYZAYODKOIQUIP-UHFFFAOYSA-N
• SMILES: Cc1cc(OCCCP(=O)(O)O)ccc1CCc1cnc2c(N)nc3cc(CCC(=O)O)ccc3c2c1

靶点实验

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实验名称：Ratio of EC50 for TLR7 in Balb/c mouse splenocytes to EC50 for human TLR7 expressed i... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3829217

实验名称：Agonist activity at human TLR8 expressed in HEK293 cells up to 30 uM incubated for 6 ... 来源：ChEMBL 靶标：Toll-like receptor 8 External Id：CHEMBL3829202

实验名称：Ratio of EC50 for TLR7 in human PBMC to EC50 for human TLR7 expressed in HEK293 cells 来源：ChEMBL 靶标：N/A External Id：CHEMBL3829218

实验名称：Reporter Gene Assay from US Patent US9597326: "Benzonapthyridine compositions and use... 来源：BindingDB 靶标：N/A External Id：BindingDB_982_1

实验名称：Agonist activity at TLR7 in Balb/c mouse splenocytes assessed as induction of IL-6 se... 来源：ChEMBL 靶标：Toll-like receptor 7 External Id：CHEMBL3829203

实验名称：Agonist activity at TLR7 in Balb/c mouse splenocytes assessed as induction of IL-6 se... 来源：ChEMBL 靶标：Toll-like receptor 7 External Id：CHEMBL3829204

实验名称：Agonist activity at human TLR7 expressed in HEK293 cells incubated for 6 hrs by lucif... 来源：ChEMBL 靶标：Toll-like receptor 7 External Id：CHEMBL3829199

实验名称：Agonist activity at human TLR7 expressed in HEK293 cells incubated for 6 hrs by lucif... 来源：ChEMBL 靶标：Toll-like receptor 7 External Id：CHEMBL3829200

实验名称：Agonist activity at TLR7 in human PBMC assessed as induction of IL-6 secretion in sup... 来源：ChEMBL 靶标：Toll-like receptor 7 External Id：CHEMBL3829205

实验名称：Agonist activity at TLR7 in human PBMC assessed as induction of IL-6 secretion in sup... 来源：ChEMBL 靶标：Toll-like receptor 7 External Id：CHEMBL3829206

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