2-[(1-Methyl-1h-Benzimidazol-2-Yl)methyl]-6-Morpholin-4-Ylpyrimidin-4(3h)-One

• 常用名: 2-[(1-Methyl-1h-Benzimidazol-2-Yl)methyl]-6-Morpholin-4-Ylpyrimidin-4(3h)-One
• 英文名: 2-[(1-Methyl-1h-Benzimidazol-2-Yl)methyl]-6-Morpholin-4-Ylpyrimidin-4(3h)-One
• CAS号: 1260544-15-7
• 分子量: 325.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₇H₁₉N₅O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-[(1-Methyl-1h-Benzimidazol-2-Yl)methyl]-6-Morpholin-4-Ylpyrimidin-4(3h)-One

物理化学性质

• 分子式: C₁₇H₁₉N₅O₂
• 分子量: 325.4
• InChIKey: XLESLWHDVUIEMT-UHFFFAOYSA-N
• SMILES: Cn1c(Cc2nc(N3CCOCC3)cc(=O)[nH]2)nc2ccccc21

靶点实验

查看更多实验

实验名称：Experimentally measured binding affinity data (IC50) for protein-ligand complexes der... 来源：Shanghai Institute of Organic Chemistry 靶标：N/A External Id：PDBbind-IC50 for protein-ligand complexes

实验名称：Antitumor activity against PTEN-deficient human PC3 cells xenografted in SCID mouse a... 来源：ChEMBL 靶标：PC-3 External Id：CHEMBL2066368

实验名称：Toxicity in SCID mouse bearing PTEN-deficient human PC3 cells at 300 mg/kg, po BID fo... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2066369

实验名称：Plasma concentration in SCID mouse xenografted with PTEN-deficient human PC3 cells at... 来源：ChEMBL 靶标：Plasma External Id：CHEMBL2066366

实验名称：Plasma concentration in SCID mouse xenografted with PTEN-deficient human PC3 cells at... 来源：ChEMBL 靶标：Plasma External Id：CHEMBL2066367

实验名称：Toxicity in SCID mouse bearing PTEN-deficient human PC3 cells assessed as weight loss... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2066370

实验名称：Inhibition of human PI3Kbeta-mediated Akt phosphorylation at Ser473 residue expressed... 来源：ChEMBL 靶标：Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform External Id：CHEMBL2066371

实验名称：Efflux ratio of permeability from apical to basolateral over basolateral to apical si... 来源：ChEMBL 靶标：Caco-2 External Id：CHEMBL3119740

实验名称：Drug metabolism in mouse liver microsomes 来源：ChEMBL 靶标：N/A External Id：CHEMBL2067914

实验名称：Inhibition of PI3Kbeta-mediated Akt phosphorylation at S473 in PTEN-deficient human P... 来源：ChEMBL 靶标：Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform External Id：CHEMBL3119743

共46条，当前第1页，共5页

1

2

3

4

5