1H-Pyrazole-4-sulfonamide, N-[(1R)-1-[4-(5-cyano-2-methoxy-3-pyridinyl)phenyl]ethyl]-1-methyl-3-(trifluoromethyl)

• 常用名: 1H-Pyrazole-4-sulfonamide, N-[(1R)-1-[4-(5-cyano-2-methoxy-3-pyridinyl)phenyl]ethyl]-1-methyl-3-(trifluoromethyl)
• 英文名: 1H-Pyrazole-4-sulfonamide, N-[(1R)-1-[4-(5-cyano-2-methoxy-3-pyridinyl)phenyl]ethyl]-1-methyl-3-(trifluoromethyl)
• CAS号: 1268486-79-8
• 分子量: 465.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₁₈F₃N₅O₃S
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 1H-Pyrazole-4-sulfonamide, N-[(1R)-1-[4-(5-cyano-2-methoxy-3-pyridinyl)phenyl]ethyl]-1-methyl-3-(trifluoromethyl)

物理化学性质

• 分子式: C₂₀H₁₈F₃N₅O₃S
• 分子量: 465.5
• InChIKey: QSPPOHUPKZMCQN-GFCCVEGCSA-N
• SMILES: COc1ncc(C#N)cc1-c1ccc(C(C)NS(=O)(=O)c2cn(C)nc2C(F)(F)F)cc1

靶点实验

查看更多实验

实验名称：Solubility of the compound in PBS at pH 7.4 来源：ChEMBL 靶标：N/A External Id：CHEMBL1646702

实验名称：Intrinsic clearance in rat liver microsomes measured per mg of protein 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL1646703

实验名称：Intrinsic clearance in human liver microsomes measured per mg of protein 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL1646706

实验名称：Oral bioavailability in Wistar rat at 10 mg/kg 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1646707

实验名称：Plasma clearance in Wistar rat at 2 mg/kg, iv; 10 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1646708

实验名称：Volume of distribution at steady state in Wistar rat at 2 mg/kg, iv; 10 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1646709

实验名称：Binding affinity to human recombinant GR by competition ligand binding fluorescence p... 来源：ChEMBL 靶标：Glucocorticoid receptor External Id：CHEMBL1646699

实验名称：Binding affinity to human recombinant PR by competition ligand binding fluorescence p... 来源：ChEMBL 靶标：Progesterone receptor External Id：CHEMBL1646700

实验名称：Selectivity ratio of pEC50 for human recombinant PR to pEC50 human recombinant GR 来源：ChEMBL 靶标：N/A External Id：CHEMBL1646701

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