5-methyl-N-tetralin-2-yl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

• 常用名: 5-methyl-N-tetralin-2-yl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
• 英文名: 5-methyl-N-tetralin-2-yl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
• CAS号: 1281860-80-7
• 分子量: 279.34
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₆H₁₇N₅
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 5-methyl-N-tetralin-2-yl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine

物理化学性质

• 分子式: C₁₆H₁₇N₅
• 分子量: 279.34
• InChIKey: BOTVJBHLFOCPPM-UHFFFAOYSA-N
• SMILES: Cc1cc(NC2CCc3ccccc3C2)n2ncnc2n1

靶点实验

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实验名称：Ratio IC50 for His6-tagged recombinant Plasmodium berghei dihydroorotate dehydrogenas... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1785547

实验名称：Aqueous solubility of the compound in phosphate buffer at pH 6.5 来源：ChEMBL 靶标：N/A External Id：CHEMBL1785549

实验名称：Partition coefficient, log D of the compound at pH 7.4 by UV-HPLC analysis 来源：ChEMBL 靶标：N/A External Id：CHEMBL1785548

实验名称：Intrinsic clearance in human liver microsome assessed per mg of protein at 1 uM after... 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL1785551

实验名称：Plasma protein binding in human by albumin chromatographic method 来源：ChEMBL 靶标：Plasma External Id：CHEMBL1785550

实验名称：Intrinsic clearance in mouse liver microsome assessed per mg of protein at 1 uM after... 来源：ChEMBL 靶标：Liver External Id：CHEMBL1785552

实验名称：Inhibition of His6-tagged recombinant Plasmodium falciparum dihydroorotate dehydrogen... 来源：ChEMBL 靶标：Dihydroorotate dehydrogenase (quinone), mitochondrial External Id：CHEMBL1785541

实验名称：Inhibition of His6-tagged recombinant human dihydroorotate dehydrogenase expressed in... 来源：ChEMBL 靶标：Dihydroorotate dehydrogenase (quinone), mitochondrial External Id：CHEMBL1785543

实验名称：Inhibition of His6-tagged recombinant Plasmodium berghei dihydroorotate dehydrogenase... 来源：ChEMBL 靶标：N/A External Id：CHEMBL1785542

实验名称：Antimalarial activity against Plasmodium falciparum 3D7 infected in human A positive ... 来源：ChEMBL 靶标：Plasmodium falciparum External Id：CHEMBL1785544

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