(3-{[1-(2,4-Difluorobenzyl)-6-oxo-1,6-dihydro-3-pyridazinyl]methy l}-5-fluoro-2-methyl-1H-indol-1-yl)acetic acid

• 常用名: (3-{[1-(2,4-Difluorobenzyl)-6-oxo-1,6-dihydro-3-pyridazinyl]methy l}-5-fluoro-2-methyl-1H-indol-1-yl)acetic acid
• 英文名: (3-{[1-(2,4-Difluorobenzyl)-6-oxo-1,6-dihydro-3-pyridazinyl]methy l}-5-fluoro-2-methyl-1H-indol-1-yl)acetic acid
• CAS号: 1297276-84-6
• 分子量: 441.40300
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₃H₁₈F₃N₃O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (3-{[1-(2,4-Difluorobenzyl)-6-oxo-1,6-dihydro-3-pyridazinyl]methy l}-5-fluoro-2-methyl-1H-indol-1-yl)acetic acid

物理化学性质

• 分子式: C₂₃H₁₈F₃N₃O₃
• 分子量: 441.40300
• 精确质量: 441.13000
• PSA: 77.12000
• LogP: 3.64740
• InChIKey: ZTPOWDSDKMQVBU-UHFFFAOYSA-N
• SMILES: Cc1c(Cc2ccc(=O)n(Cc3ccc(F)cc3F)n2)c2cc(F)ccc2n1CC(=O)O

靶点实验

查看更多实验

实验名称：AUC (0 to infinity) in rat at 10 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2211737

实验名称：Volume of distribution at steady state in rat at 2 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2212192

实验名称：Antiinflammatory activity in house dust mite-induced airway allergy BALB/c mouse mode... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2211728

实验名称：Antiinflammatory activity in house dust mite-induced airway allergy BALB/c mouse mode... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2211729

实验名称：Antiinflammatory activity in house dust mite-induced airway allergy BALB/c mouse mode... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2211726

实验名称：Antiinflammatory activity in house dust mite-induced airway allergy BALB/c mouse mode... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2211727

实验名称：Antiinflammatory activity in CRTH2-knock out oxazolone induced contact hypersensitivi... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2211732

实验名称：Oral bioavailability in rat at 10 mg/kg 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2211733

实验名称：Antiinflammatory activity in house dust mite-induced airway allergy BALB/c mouse mode... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2211730

实验名称：Antiinflammatory activity in po dosed CRTH2-knock out oxazolone induced contact hyper... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2211731

共71条，当前第1页，共8页

1

2

3

4

5

英文别名

• 2-(2-trifluoromethyl-phenylsulfamoyl)-benzoic acid methyl ester
• Benzoic acid,2-[[[2-(trifluoromethyl)phenyl]amino]sulfonyl]-,methyl ester
• 2-(3-((1-(2,4-difluorobenzyl)-6-oxo-1,6-dihydropyridazin-3-yl)methyl)-5-fluoro-2-methyl-1H-indol-1-yl)acetic acid