N-[[4-(3-methylphenyl)phenyl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide

• 常用名: N-[[4-(3-methylphenyl)phenyl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
• 英文名: N-[[4-(3-methylphenyl)phenyl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide
• CAS号: 1314795-68-0
• 分子量: 395.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₆H₂₅N₃O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-[[4-(3-methylphenyl)phenyl]methyl]-4-(1,8-naphthyridin-2-yl)butanamide

物理化学性质

• 分子式: C₂₆H₂₅N₃O
• 分子量: 395.5
• InChIKey: PPGSCVIDQKFZTG-UHFFFAOYSA-N
• SMILES: Cc1cccc(-c2ccc(CNC(=O)CCCc3ccc4cccnc4n3)cc2)c1

靶点实验

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实验名称：Intrinsic clearance in rat liver microsomes preincubated for 5 mins before addition o... 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL2155421

实验名称：Antagonist activity at human GPR91 receptor expressed in CHO-K1 cells co-expressing G... 来源：ChEMBL 靶标：Succinate receptor 1 External Id：CHEMBL2156127

实验名称：ASTRAZENECA: % bound to plasma by equilibrium dialysis. Compound is incubated with wh... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301368

实验名称：AUC (0 to 8 hrs) in Wistar rat plasma at 50 mg/kg, ip 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2155431

实验名称：ASTRAZENECA: Intrinsic clearance measured in human hepatocytes following incubation a... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3301372

实验名称：Cmax in Wistar rat at 5 mg/kg, iv by LC/MS/MS analysis 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2155425

实验名称：Hypotensive activity in Wistar rat assessed as inhibition of succinate-induced increa... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2155521

实验名称：Plasma clearance in Wistar rat at 5 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2155426

实验名称：Antagonist activity at rat GPR91 receptor expressed in CHO-K1 cells co-expressing Gal... 来源：ChEMBL 靶标：Succinate receptor 1 External Id：CHEMBL2155423

实验名称：Hypotensive activity in Wistar rat assessed as inhibition of succinate-induced increa... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2155520

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