4-[3-(2-{3-Cyano-4-[(1-methylethyl)oxy]phenyl}-5-pyrimidinyl)-2-ethylphenyl]butanoic acid

• 常用名: 4-[3-(2-{3-Cyano-4-[(1-methylethyl)oxy]phenyl}-5-pyrimidinyl)-2-ethylphenyl]butanoic acid
• 英文名: 4-[3-(2-{3-Cyano-4-[(1-methylethyl)oxy]phenyl}-5-pyrimidinyl)-2-ethylphenyl]butanoic acid
• CAS号: 1334606-48-2
• 分子量: 429.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₆H₂₇N₃O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 4-[3-(2-{3-Cyano-4-[(1-methylethyl)oxy]phenyl}-5-pyrimidinyl)-2-ethylphenyl]butanoic acid

物理化学性质

• 分子式: C₂₆H₂₇N₃O₃
• 分子量: 429.5
• InChIKey: KGURPWIBPCCLDK-UHFFFAOYSA-N
• SMILES: CCc1c(CCCC(=O)O)cccc1-c1cnc(-c2ccc(OC(C)C)c(C#N)c2)nc1

靶点实验

查看更多实验

实验名称：AUC (0 to 24 hrs) in mouse 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2061889

实验名称：Ratio of drug level in brain to blood in C57BL/6 mouse at 2 mg/kg, ip after 1 hr 来源：ChEMBL 靶标：Nucleic Acid External Id：CHEMBL2061663

实验名称：Percentage unbound in human plasma 来源：ChEMBL 靶标：Plasma External Id：CHEMBL2061661

实验名称：Oral bioavailability in mouse 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2061666

实验名称：Ratio of drug level in brain to blood in C57BL/6 mouse at 2 mg/kg, ip after 4 hrs 来源：ChEMBL 靶标：Nucleic Acid External Id：CHEMBL2061664

实验名称：Half life in mouse 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2061665

实验名称：Permeability of the compound 来源：ChEMBL 靶标：N/A External Id：CHEMBL2061654

实验名称：Agonist activity against S1P1 receptor by cell based FRET assay 来源：ChEMBL 靶标：Sphingosine 1-phosphate receptor 1 External Id：CHEMBL2061652

实验名称：Agonist activity against S1P3 receptor by cell based FRET assay 来源：ChEMBL 靶标：Sphingosine 1-phosphate receptor 3 External Id：CHEMBL2061653

实验名称：Inhibition of CYP2D6 来源：ChEMBL 靶标：Cytochrome P450 2D6 External Id：CHEMBL2061659

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