5-(6-Phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylmethyl)-2H-isoquinolin-1-one

• 常用名: 5-(6-Phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylmethyl)-2H-isoquinolin-1-one
• 英文名: 5-(6-Phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylmethyl)-2H-isoquinolin-1-one
• CAS号: 1350612-75-7
• 分子量: 353.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₁H₁₅N₅O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 5-(6-Phenyl-[1,2,4]triazolo[4,3-b]pyridazin-3-ylmethyl)-2H-isoquinolin-1-one

物理化学性质

• 分子式: C₂₁H₁₅N₅O
• 分子量: 353.4
• InChIKey: UKMNXWVOVNJJBT-UHFFFAOYSA-N
• SMILES: C1=CC=C(C=C1)C2=NN3C(=NN=C3CC4=C5C=CNC(=O)C5=CC=C4)C=C2

靶点实验

查看更多实验

实验名称：Inhibition of recombinant c-met by HTRF assay 来源：ChEMBL 靶标：Hepatocyte growth factor receptor External Id：CHEMBL1925561

实验名称：Growth inhibition of c-met-amplified human SNU5 cells after 72 hrs by MTS assay 来源：ChEMBL 靶标：SNU-5 External Id：CHEMBL1925567

实验名称：Growth inhibition of c-met-amplified human MKN45 cells after 72 hrs by MTS assay 来源：ChEMBL 靶标：MKN-45 External Id：CHEMBL1925566

实验名称：Growth inhibition of c-met-independent human NCI-N87 cells after 72 hrs by MTS assay 来源：ChEMBL 靶标：NCI-N87 External Id：CHEMBL1925569

实验名称：Growth inhibition of c-met-amplified human Hs 746T cells after 72 hrs by MTS assay 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL1925568

实验名称：AUC in rat at 10 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1925571

实验名称：Clearance in rat at 10 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1925573

实验名称：AUC in rat at 10 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1925572

实验名称：Volume of distribution at steady state in rat at 10 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1925575

实验名称：Oral bioavailability in rat at 10 mg/kg 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL1925574

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