N-(3-Fluorophenyl)-5-(6-methyl-2-pyridinyl)-4-[1,2,4]triazolo[1,5-a]pyridin-6-yl-1H-imidazole-2-methanamine

• 常用名: N-(3-Fluorophenyl)-5-(6-methyl-2-pyridinyl)-4-[1,2,4]triazolo[1,5-a]pyridin-6-yl-1H-imidazole-2-methanamine
• 英文名: N-(3-Fluorophenyl)-5-(6-methyl-2-pyridinyl)-4-[1,2,4]triazolo[1,5-a]pyridin-6-yl-1H-imidazole-2-methanamine
• CAS号: 1352608-83-3
• 分子量: 399.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₂H₁₈FN₇
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-(3-Fluorophenyl)-5-(6-methyl-2-pyridinyl)-4-[1,2,4]triazolo[1,5-a]pyridin-6-yl-1H-imidazole-2-methanamine

物理化学性质

• 分子式: C₂₂H₁₈FN₇
• 分子量: 399.4
• InChIKey: COZUKVUBSCQZGM-UHFFFAOYSA-N
• SMILES: Cc1cccc(-c2[nH]c(CNc3cccc(F)c3)nc2-c2ccc3ncnn3c2)n1

靶点实验

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实验名称：Inhibition of human recombinant p38alpha expressed in Escherichia coli using ATF2 as ... 来源：ChEMBL 靶标：Mitogen-activated protein kinase 14 External Id：CHEMBL3268789

实验名称：Inhibition of human recombinant ALK5 expressed in insect Sf9 cells using casein as su... 来源：ChEMBL 靶标：TGF-beta receptor type-1 External Id：CHEMBL3268788

实验名称：Inhibition of ALK5 in human HaCaT cells assessed as residual activity at 0.03 uM afte... 来源：ChEMBL 靶标：TGF-beta receptor type-1 External Id：CHEMBL3268791

实验名称：Selectivity index, ratio of IC50 for human recombinant p38alpha to IC50 for human rec... 来源：ChEMBL 靶标：N/A External Id：CHEMBL3268790

实验名称：Solubility of the compound in aqueous buffer at pH 6.8 after 24 hrs 来源：ChEMBL 靶标：N/A External Id：CHEMBL3268793

实验名称：Solubility of the compound in aqueous buffer at pH 1.2 after 24 hrs 来源：ChEMBL 靶标：N/A External Id：CHEMBL3268792

实验名称：Cell-Free Assay for Evaluating Inhibition of ALK5 Kinase Phosphorylatio from US Paten... 来源：BindingDB 靶标：N/A External Id：BindingDB_1037_1

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