6-fluoro-7-methoxy-2-methyl-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]-1H-quinolin-4-one

• 常用名: 6-fluoro-7-methoxy-2-methyl-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]-1H-quinolin-4-one
• 英文名: 6-fluoro-7-methoxy-2-methyl-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]-1H-quinolin-4-one
• CAS号: 1354745-69-9
• 分子量: 459.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₄H₁₇F₄NO₄
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 6-fluoro-7-methoxy-2-methyl-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]-1H-quinolin-4-one

物理化学性质

• 分子式: C₂₄H₁₇F₄NO₄
• 分子量: 459.4
• InChIKey: SUFFMIUELDDRLM-UHFFFAOYSA-N
• SMILES: COc1cc2[nH]c(C)c(-c3ccc(Oc4ccc(OC(F)(F)F)cc4)cc3)c(=O)c2cc1F

靶点实验

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实验名称：Metabolic stability in human liver microsomes 来源：ChEMBL 靶标：Liver microsome External Id：CHEMBL3266501

实验名称：Metabolic stability in rat liver microsomes 来源：ChEMBL 靶标：Liver microsome External Id：CHEMBL3266500

实验名称：Antimalarial activity against chloroquine-sensitive Plasmodium falciparum D6 MRA-285 ... 来源：ChEMBL 靶标：Plasmodium falciparum External Id：CHEMBL3266493

实验名称：Antimalarial activity against atovaquone-resistant clinical isolate Plasmodium falcip... 来源：ChEMBL 靶标：Plasmodium falciparum External Id：CHEMBL3266495

实验名称：Antiparasitic activity against Toxoplasma gondii infected in CF-1 mouse at 0.04 to 50... 来源：ChEMBL 靶标：Toxoplasma gondii External Id：CHEMBL4403512

实验名称：Antimalarial activity against multidrug-resistant Plasmodium falciparum Dd2 MRA-156 i... 来源：ChEMBL 靶标：NON-PROTEIN TARGET External Id：CHEMBL3266494

实验名称：Therapeutic index, ratio of TD50 in CF-1 mouse to IC50 of Toxoplasma gondii infected ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4403514

实验名称：Cytotoxicity against human HepG2 cells after 24 hrs incubation by Alamar Blue assay 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL3266496

实验名称：Antimalarial activity against Plasmodium yoelii MR4 MRA-428 infected in mouse CF1 ass... 来源：ChEMBL 靶标：Plasmodium yoelii External Id：CHEMBL3266499

实验名称：Antimalarial activity against Plasmodium yoelii MR4 MRA-428 infected in mouse CF1 ass... 来源：ChEMBL 靶标：Plasmodium yoelii External Id：CHEMBL3266498

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