N-(5-methoxy-1H-indol-6-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

• 常用名: N-(5-methoxy-1H-indol-6-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
• 英文名: N-(5-methoxy-1H-indol-6-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide
• CAS号: 1356014-46-4
• 分子量: 307.31
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₆H₁₃N₅O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-(5-methoxy-1H-indol-6-yl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

物理化学性质

• 分子式: C₁₆H₁₃N₅O₂
• 分子量: 307.31
• InChIKey: PEDDPGPEKWMKNW-UHFFFAOYSA-N
• SMILES: COc1cc2cc[nH]c2cc1NC(=O)c1cnn2cccnc12

靶点实验

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实验名称：In vitro IRAK-1 and IRAK-4 Assay from US Patent US9255110: "Pyrazolo[1,5a]pyrimidine ... 来源：BindingDB 靶标：N/A External Id：BindingDB_7617_1

实验名称：Inhibition of recombinant IRAK4 (unknown origin) using KKARFSRFAGSSPSQSSMVAR as subst... 来源：ChEMBL 靶标：Interleukin-1 receptor-associated kinase 4 External Id：CHEMBL4360009

实验名称：Inhibition of IRAK4 in human THP1-Xblue-MD2-CD14 cells assessed as reduction in LPS-i... 来源：ChEMBL 靶标：Interleukin-1 receptor-associated kinase 4 External Id：CHEMBL4359943

实验名称：Inhibition of human recombinant full length N-terminal His6-tagged IRAK1 (Argl94 to S... 来源：ChEMBL 靶标：Interleukin-1 receptor-associated kinase 1 External Id：CHEMBL4359941

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