4-amino-2-(4-ethylpiperazino)-N~5~-phenyl-5-pyrimidinecarboxamide

• 常用名: 4-amino-2-(4-ethylpiperazino)-N~5~-phenyl-5-pyrimidinecarboxamide
• 英文名: 4-amino-2-(4-ethylpiperazino)-N~5~-phenyl-5-pyrimidinecarboxamide
• CAS号: 1358217-27-2
• 分子量: 326.4
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₇H₂₂N₆O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 4-amino-2-(4-ethylpiperazino)-N~5~-phenyl-5-pyrimidinecarboxamide

物理化学性质

• 分子式: C₁₇H₂₂N₆O
• 分子量: 326.4
• InChIKey: VNTUQTXJUJKPJK-UHFFFAOYSA-N
• SMILES: CCN1CCN(c2ncc(C(=O)Nc3ccccc3)c(N)n2)CC1

靶点实验

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实验名称：Inhibition of human SHP2 in human NCI-H1975 cells assessed as reduction in ERK phosph... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 11 External Id：CHEMBL5362718

实验名称：Inhibition of colony formation in human NCI-H1975 cells at 10 uM incubated for 14 day... 来源：ChEMBL 靶标：NCI-H1975 External Id：CHEMBL5362719

实验名称：Inhibition of human SHP2 in human NCI-H1975 cells assessed as reduction in ERK phosph... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 11 External Id：CHEMBL5362716

实验名称：Inhibition of pIRS-1 peptide activated human SHP2 T253M/Q257L mutant using DiFMUP as ... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 11 External Id：CHEMBL5362714

实验名称：Inhibition of pIRS-1 peptide activated human SHP2 E76K mutant using DiFMUP as substra... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 11 External Id：CHEMBL5362715

实验名称：Inhibition of pIRS-1 peptide activated human wild type SHP2 FL (Met1 to Leu525 residu... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 11 External Id：CHEMBL5362712

实验名称：Primary screen in NF54 nanoGlo assay, in single point, at 2uM, 72h 来源：ChEMBL 靶标：Plasmodium falciparum External Id：CHEMBL4888485

实验名称：Inhibition of pIRS-1 peptide activated truncated human SHP2 PTP (Ala-237-Ile-529 resi... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 11 External Id：CHEMBL5362713

实验名称：Inhibition of pIRS-1 peptide activated human wild type SHP2 FL (Met1 to Leu525 residu... 来源：ChEMBL 靶标：Tyrosine-protein phosphatase non-receptor type 11 External Id：CHEMBL5362711

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