N-{4-[(6,7-Dimethoxyquinolin-4-Yl)oxy]-3-Fluorophenyl}-1,5-Dimethyl-3-Oxo-2-Phenyl-2,3-Dihydro-1h-Pyrazole-4-Carboxamide

• 常用名: N-{4-[(6,7-Dimethoxyquinolin-4-Yl)oxy]-3-Fluorophenyl}-1,5-Dimethyl-3-Oxo-2-Phenyl-2,3-Dihydro-1h-Pyrazole-4-Carboxamide
• 英文名: N-{4-[(6,7-Dimethoxyquinolin-4-Yl)oxy]-3-Fluorophenyl}-1,5-Dimethyl-3-Oxo-2-Phenyl-2,3-Dihydro-1h-Pyrazole-4-Carboxamide
• CAS号: 1361235-52-0
• 分子量: 528.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₉H₂₅FN₄O₅
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-{4-[(6,7-Dimethoxyquinolin-4-Yl)oxy]-3-Fluorophenyl}-1,5-Dimethyl-3-Oxo-2-Phenyl-2,3-Dihydro-1h-Pyrazole-4-Carboxamide

物理化学性质

• 分子式: C₂₉H₂₅FN₄O₅
• 分子量: 528.5
• InChIKey: SBLMCLDRWJNEJK-UHFFFAOYSA-N
• SMILES: COc1cc2nccc(Oc3ccc(NC(=O)c4c(C)n(C)n(-c5ccccc5)c4=O)cc3F)c2cc1OC

靶点实验

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实验名称：Inhibition of HGF-mediated c-met autophosphorylation in po dosed Balb/c mouse liver a... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2032496

实验名称：Inhibition of HGF-mediated c-met autophosphorylation in Balb/c mouse liver at 10 mg/k... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2032497

实验名称：AUC in Sprague-Dawley rat at 5 mg/kg, po 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2032494

实验名称：Inhibition of HGF-mediated c-met autophosphorylation in po dosed Balb/c mouse liver c... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL2032495

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实验名称：Clearance in Sprague-Dawley rat at 2 mg/kg, iv 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2032489

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实验名称：Inhibition of VEGFR2 by HTRF assay 来源：ChEMBL 靶标：Vascular endothelial growth factor receptor 2 External Id：CHEMBL2032454

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