1-hydroxy-3,4-bis(1H-indol-3-yl)pyrrole-2,5-dione

• 常用名: 1-hydroxy-3,4-bis(1H-indol-3-yl)pyrrole-2,5-dione
• 英文名: 1-hydroxy-3,4-bis(1H-indol-3-yl)pyrrole-2,5-dione
• CAS号: 137108-08-8
• 分子量: 343.33600
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₀H₁₃N₃O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 1-hydroxy-3,4-bis(1H-indol-3-yl)pyrrole-2,5-dione

物理化学性质

• 分子式: C₂₀H₁₃N₃O₃
• 分子量: 343.33600
• 精确质量: 343.09600
• PSA: 89.19000
• LogP: 3.25590
• InChIKey: STOYHVQKKWVYFE-UHFFFAOYSA-N
• SMILES: O=C1C(c2c[nH]c3ccccc23)=C(c2c[nH]c3ccccc23)C(=O)N1O

靶点实验

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实验名称：Induction of Streptococcus pneumoniae VicK aggregation up to 500 uM in presence of gl... 来源：ChEMBL 靶标：Sensor protein kinase WalK External Id：CHEMBL4271588

实验名称：Induction of Thermotoga maritima HK853 aggregation up to 500 uM in presence of glutar... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4271587

实验名称：Inhibition of rat brain protein kinase C (PKC) with ATP and histone as substrates 来源：ChEMBL 靶标：Protein kinase C gamma type External Id：CHEMBL769176

实验名称：PKC assay from Article 10.1021/jm00079a024: "Inhibitors of protein kinase C. 1. 2,3-B... 来源：BindingDB 靶标：N/A External Id：BindingDB_445_1

实验名称：Screen for IRF3 induction in PMA-stimulated THP1 cells. 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：N/A External Id：HMS1209_GSK-Roche

实验名称：Inhibition of ADP-BODIPY binding to Thermotoga maritima HK853 in presence of Triton X... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4271580

实验名称：Inhibition of ADP-BODIPY binding to Thermotoga maritima HK853 by fluorescence polariz... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4271579

实验名称：Inhibition of ADP-BODIPY binding to Thermotoga maritima HK853 at 100 uM by fluorescen... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4271581

实验名称：A screen for known kinase inhibitors that affect the stability of GFP-p53 in an HPV16... 来源：ICCB-Longwood/NSRB Screening Facility, Harvard Medical School 靶标：Cellular tumor antigen p53 External Id：HMS1119_GSK-Roche

实验名称：Discovering small molecule activators of G protein-gated inwardly-rectifying potassiu... 来源：15621 靶标：G protein-activated inward rectifier potassium channel 2 External Id：VANDERBILT_HTS_GIRK2_MPD

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英文别名

• Bisindolylmaleimide deriv. 11
• 1H-Pyrrole-2,5-dione,1-hydroxy-3,4-di-1H-indol-3-yl
• HMS3401H13
• 1-Hydroxy-2,3-bis(3-indolyl)-3-pyrrolin-2,5-dione
• 1-hydroxy-3,4-bis(3-indolyl)-2,5-pyrroledione