4-amino-5-chloro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one

• 常用名: 4-amino-5-chloro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
• 英文名: 4-amino-5-chloro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one
• CAS号: 137530-42-8
• 分子量: 263.70100
• 密度: 1.86g/cm3
• 沸点: 476.8ºC at 760mmHg
• 分子式: C₈H₁₀ClN₃O₃S
• 熔点: N/A
• 闪点: 242.2ºC

名称

• 英文名: 4-amino-5-chloro-1-[(2S,5R)-2-(hydroxymethyl)-1,3-oxathiolan-5-yl]pyrimidin-2-one

物理化学性质

• 密度: 1.86g/cm3
• 沸点: 476.8ºC at 760mmHg
• 分子式: C₈H₁₀ClN₃O₃S
• 分子量: 263.70100
• 闪点: 242.2ºC
• 精确质量: 263.01300
• PSA: 116.66000
• LogP: 0.40170
• InChIKey: SUAKTABSHMTKSV-RITPCOANSA-N
• SMILES: Nc1nc(=O)n(C2CSC(CO)O2)cc1Cl
• 蒸汽压: 4.27E-11mmHg at 25°C
• 折射率: 1.768

靶点实验

查看更多实验

实验名称：Percent inhibition for its anti-HBV activity in infected HepG2(2.2.15) cells at conce... 来源：ChEMBL 靶标：HepG2 External Id：CHEMBL694139

实验名称：Compound was tested for its anti-HIV activity in acutely infected MT-4 cells 来源：ChEMBL 靶标：MT4 External Id：CHEMBL713253

实验名称：Inhibition of cell growth against HIV-1 infected PBM (Human peripheral blood mononucl... 来源：ChEMBL 靶标：Human immunodeficiency virus 1 External Id：CHEMBL757967

实验名称：Compound was tested for its anti-HIV activity against HIV-1 LAI in human peripheral b... 来源：ChEMBL 靶标：N/A External Id：CHEMBL758939

实验名称：Inhibition of cell growth in vero cells 来源：ChEMBL 靶标：Vero External Id：CHEMBL873390

实验名称：Compound was tested for its cytotoxic activity in uninfected human peripheral blood m... 来源：ChEMBL 靶标：N/A External Id：CHEMBL757800

实验名称：Concentration required for antiviral activity in PBMC (human peripheral blood mononuc... 来源：ChEMBL 靶标：Human immunodeficiency virus 1 External Id：CHEMBL759088

实验名称：Compound was tested for its cytotoxic activity in uninfected Vero cells 来源：ChEMBL 靶标：Vero External Id：CHEMBL820901

实验名称：HIV Cellular Data 来源：NIAID 靶标：N/A External Id：HIV Cellular Data

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英文别名

• (+/-)-5-ClSddC
• (+)-(2S,5R)-5-Chloro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)cytosine
• 2(1H)-Pyrimidinone,4-amino-5-chloro-1-(2-(hydroxymethyl)-1,3-oxathiolan-5-yl)-,(2S-cis)