4-[2-(1H-indol-4-yloxy)-3-pyridinyl]-6-methyl-2-pyrimidinamine

• 常用名: 4-[2-(1H-indol-4-yloxy)-3-pyridinyl]-6-methyl-2-pyrimidinamine
• 英文名: 4-[2-(1H-indol-4-yloxy)-3-pyridinyl]-6-methyl-2-pyrimidinamine
• CAS号: 1379860-56-6
• 分子量: 317.3
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₁₅N₅O
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 4-[2-(1H-indol-4-yloxy)-3-pyridinyl]-6-methyl-2-pyrimidinamine

物理化学性质

• 分子式: C₁₈H₁₅N₅O
• 分子量: 317.3
• InChIKey: MMIJETCSDONNGS-UHFFFAOYSA-N
• SMILES: Cc1cc(-c2cccnc2Oc2cccc3[nH]ccc23)nc(N)n1

靶点实验

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实验名称：Inhibition of human N-terminal poly-His tagged-PI3Kgamma expressed in Sf9 baculovirus... 来源：ChEMBL 靶标：Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform External Id：CHEMBL2166655

实验名称：Inhibition of human N-terminal poly-His tagged-PI3Kbeta expressed in Sf9 baculovirus ... 来源：ChEMBL 靶标：Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform External Id：CHEMBL2166656

实验名称：Inhibition of human N-terminal poly-His tagged-PI3Kdelta expressed in Sf9 baculovirus... 来源：ChEMBL 靶标：Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform External Id：CHEMBL2166654

实验名称：Inhibition of Phosphatidylinositol 3-kinase pathway in PTEN-deficient human U87MG cel... 来源：ChEMBL 靶标：N/A External Id：CHEMBL2169663

实验名称：Inhibition of recombinant GST-tagged mTOR-mediated 4EBP1 phosphorylation after 90 min... 来源：ChEMBL 靶标：Serine/threonine-protein kinase mTOR External Id：CHEMBL2169664

实验名称：Inhibition of human N-terminal poly-His tagged-PI3Kalpha expressed in Sf9 baculovirus... 来源：ChEMBL 靶标：Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform External Id：CHEMBL2166657

实验名称：Inhibition of B-Raf V600E mutant 来源：ChEMBL 靶标：Serine/threonine-protein kinase B-raf External Id：CHEMBL2169661

实验名称：Intrinsic clearance in rat liver microsomes 来源：ChEMBL 靶标：Liver microsomes External Id：CHEMBL2169662

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