N-[5-(2-chlorobenzoyl)-4-(3-chlorophenyl)thiophen-2-yl]-2-(4-ethylsulfonylphenyl)acetamide

• 常用名: N-[5-(2-chlorobenzoyl)-4-(3-chlorophenyl)thiophen-2-yl]-2-(4-ethylsulfonylphenyl)acetamide
• 英文名: N-[5-(2-chlorobenzoyl)-4-(3-chlorophenyl)thiophen-2-yl]-2-(4-ethylsulfonylphenyl)acetamide
• CAS号: 1391981-64-8
• 分子量: 558.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₇H₂₁Cl₂NO₄S₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: N-[5-(2-chlorobenzoyl)-4-(3-chlorophenyl)thiophen-2-yl]-2-(4-ethylsulfonylphenyl)acetamide

物理化学性质

• 分子式: C₂₇H₂₁Cl₂NO₄S₂
• 分子量: 558.5
• InChIKey: PDIFKINHSRCGJM-UHFFFAOYSA-N
• SMILES: CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(-c3cccc(Cl)c3)c(C(=O)c3ccccc3Cl)s2)cc1

靶点实验

查看更多实验

实验名称：Oral biavailability in C57BL/6 mouse at 2 mg/kg 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3106073

实验名称：Dose normalized AUC (0 to infinity) in C57BL/6 mouse at 2 mg/kg, po 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3106074

实验名称：Dose normalized AUC (0 to infinity) in C57BL/6 mouse at 1 mg/kg, iv 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3106078

实验名称：Half life in C57BL/6 mouse at 1 mg/kg, iv 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3106080

实验名称：Clearance in C57BL/6 mouse at 1 mg/kg, iv 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3106081

实验名称：Binding affinity to RORgammat receptor ligand binding domain (unknown origin) assesse... 来源：ChEMBL 靶标：Nuclear receptor ROR-gamma External Id：CHEMBL3106082

实验名称：Cytotoxicity in human Th17 cells assessed as effect on cell viability by cell-titer-G... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4151893

实验名称：Cytotoxicity in human Th17 cells assessed as effect on cell viability by cell-titer-G... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4151894

实验名称：Permeability from apical to basolateral side in human Caco2 cells 来源：ChEMBL 靶标：N/A External Id：CHEMBL4151895

实验名称：Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21... 来源：ChEMBL 靶标：Nuclear receptor ROR-gamma External Id：CHEMBL3369179

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