(2z,6s)-6-{3-Chloro-5-[5-(Prop-1-Yn-1-Yl)pyridin-3-Yl]thiophen-2-Yl}-2-Imino-3,6-Dimethyltetrahydropyrimidin-4(1h)-One

• 常用名: (2z,6s)-6-{3-Chloro-5-[5-(Prop-1-Yn-1-Yl)pyridin-3-Yl]thiophen-2-Yl}-2-Imino-3,6-Dimethyltetrahydropyrimidin-4(1h)-One
• 英文名: (2z,6s)-6-{3-Chloro-5-[5-(Prop-1-Yn-1-Yl)pyridin-3-Yl]thiophen-2-Yl}-2-Imino-3,6-Dimethyltetrahydropyrimidin-4(1h)-One
• CAS号: 1392015-19-8
• 分子量: 372.9
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₈H₁₇ClN₄OS
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: (2z,6s)-6-{3-Chloro-5-[5-(Prop-1-Yn-1-Yl)pyridin-3-Yl]thiophen-2-Yl}-2-Imino-3,6-Dimethyltetrahydropyrimidin-4(1h)-One

物理化学性质

• 分子式: C₁₈H₁₇ClN₄OS
• 分子量: 372.9
• InChIKey: IJYPXSRDUPWKPB-SFHVURJKSA-N
• SMILES: CC#Cc1cncc(-c2cc(Cl)c(C3(C)CC(=O)N(C)C(N)=N3)s2)c1

靶点实验

查看更多实验

实验名称：Dissociation constant, pKa of the compound 来源：ChEMBL 靶标：N/A External Id：CHEMBL2155083

实验名称：Antialzheimer activity in po dosed Sprague-Dawley rat assessed as reduction of amyloi... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2155080

实验名称：Antialzheimer activity in po dosed Sprague-Dawley rat assessed as reduction of amyloi... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL2155081

实验名称：Lipophilicity, log D of the compound 来源：ChEMBL 靶标：N/A External Id：CHEMBL2155084

实验名称：Ratio of drug level in brain to plasma in Sprague-Dawley rat at 0.1 to 100 mg/kg, po ... 来源：ChEMBL 靶标：Nucleic Acid External Id：CHEMBL2155085

实验名称：Fraction unbound in rat plasma at 10 uM after 4 hrs by rapid equilibrium dialysis ass... 来源：ChEMBL 靶标：Plasma External Id：CHEMBL2155074

实验名称：Fraction unbound in human plasma at 10 uM after 4 hrs by rapid equilibrium dialysis a... 来源：ChEMBL 靶标：Plasma External Id：CHEMBL2155075

实验名称：Apparent permeability across apical to basolateral side in human Caco2 cells at 1 to ... 来源：ChEMBL 靶标：Caco-2 External Id：CHEMBL3268104

实验名称：Intrinsic clearance in rat hepatocytes assessed per 10'6 cells at 1 uM up to 180 mins 来源：ChEMBL 靶标：Hepatocyte External Id：CHEMBL2155072

实验名称：Antialzheimer activity in CD rat brain cortex assessed as reduction of amyloid beta (... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3268103

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