2-PyridinecarboxaMide, N-(5-fluoro-2-pyridinyl)-4-[(5-fluoro-3-pyridinyl)oxy]-6-Methyl

• 常用名: 2-PyridinecarboxaMide, N-(5-fluoro-2-pyridinyl)-4-[(5-fluoro-3-pyridinyl)oxy]-6-Methyl
• 英文名: 2-PyridinecarboxaMide, N-(5-fluoro-2-pyridinyl)-4-[(5-fluoro-3-pyridinyl)oxy]-6-Methyl
• CAS号: 1396337-17-9
• 分子量: 342.30
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₇H₁₂F₂N₄O₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 2-PyridinecarboxaMide, N-(5-fluoro-2-pyridinyl)-4-[(5-fluoro-3-pyridinyl)oxy]-6-Methyl

物理化学性质

• 分子式: C₁₇H₁₂F₂N₄O₂
• 分子量: 342.30
• InChIKey: MBSANIMQXDBICP-UHFFFAOYSA-N
• SMILES: Cc1cc(Oc2cncc(F)c2)cc(C(=O)Nc2ccc(F)cn2)n1

靶点实验

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实验名称：Fraction unbound in mouse brain at 5 uM after 6 hrs by equilibrium dialysis assay 来源：ChEMBL 靶标：Brain External Id：CHEMBL4039226

实验名称：MRT in Sprague-Dawley rat at 1 mg/kg, iv up to 24 hrs post dose by LC/MS/MS analysis 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL4039223

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实验名称：Plasma clearance in Sprague-Dawley rat at 1 mg/kg, iv up to 24 hrs post dose by LC/MS... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL4039224

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实验名称：Terminal half life in Sprague-Dawley rat at 1 mg/kg, iv up to 24 hrs post dose by LC/... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL4039222

实验名称：Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate pr... 来源：ChEMBL 靶标：Cytochrome P450 2D6 External Id：CHEMBL4039219

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实验名称：Ratio of unbound drug level in Sprague-Dawley rat brain to IC50 for rat mGlu5 express... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4039233

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