VU0531245

• 常用名: VU0531245
• 英文名: VU0531245
• CAS号: 1396749-92-0
• 分子量: 391.46
• 密度: N/A
• 沸点: N/A
• 分子式: C₁₇H₁₇N₃O₄S₂
• 熔点: N/A
• 闪点: N/A

VU0531245用途

VU0531245 是一种 SLACK 通道抑制剂 (IC50: 2.1 μM)。

VU0531245名称

• 英文名: VU0531245

VU0531245生物活性

• 描述: VU0531245 是一种 SLACK 通道抑制剂 (IC50: 2.1 μM)。
• 相关类别:
  研究领域 >> 其他
  信号通路 >> 其他 >> 其他
• 参考文献:

  [1]. Qunies AM, et al. Design, synthesis, and biological evaluation of a novel series of 1,2,4-oxadiazole inhibitors of SLACK potassium channels: Identification of in vitro tool VU0935685. Bioorg Med Chem. 2023 Sep 30;95:117487.

VU0531245物理化学性质

• 分子式: C₁₇H₁₇N₃O₄S₂
• 分子量: 391.46
• InChIKey: UYJLDNIBTMAYRB-UHFFFAOYSA-N
• SMILES: CCOc1ccccc1S(=O)(=O)N1CC(c2nc(-c3ccsc3)no2)C1

VU0531245靶点实验

查看更多实验

实验名称：Plasma protein binding in mouse assessed as unbound fraction by equilibrium dialysis ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5391121

实验名称：Metabolic stability in mouse liver microsomes assessed as compound remaining measured... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5391120

实验名称：Inhibition of wild-type human SLACK expressed in CHO cells assessed as efficacy at 30... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5391118

实验名称：Inhibition of wild-type human SLACK expressed in CHO cells by whole cell voltage clam... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5391117

实验名称：Inhibition of Maxi-K (unknown origin) expressed in HEK293 cells assessed as efficacy ... 来源：ChEMBL 靶标：Calcium-activated potassium channel subunit alpha-1 External Id：CHEMBL5391116

实验名称：Inhibition of Maxi-K (unknown origin) expressed in HEK293 cells by thallium flux assa... 来源：ChEMBL 靶标：Calcium-activated potassium channel subunit alpha-1 External Id：CHEMBL5391115

实验名称：Inhibition of SLICK (unknown origin) expressed in HEK293 cells assessed as efficacy a... 来源：ChEMBL 靶标：Potassium channel subfamily T member 2 External Id：CHEMBL5391114

实验名称：Inhibition of SLICK (unknown origin) expressed in HEK293 cells by thallium flux assay 来源：ChEMBL 靶标：Potassium channel subfamily T member 2 External Id：CHEMBL5391113

实验名称：Inhibition of human SLACK A934T mutant expressed in HEK293 cells assessed as efficacy... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5391112

实验名称：Inhibition of human SLACK A934T mutant expressed in HEK293 cells by thallium flux ass... 来源：ChEMBL 靶标：N/A External Id：CHEMBL5391111

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