CC-90001

更新时间：2025-08-25 20:03:38

CC-90001结构式	常用名	CC-90001	英文名	CC-90001
	CAS号	1403859-14-2	分子量	321.42
	密度	N/A	沸点	N/A
	分子式	C₁₆H₂₇N₅O₂	熔点	N/A
	MSDS	N/A	闪点	N/A

CC-90001用途

CC-90001是一种高效、选择性和口服活性的c-junn末端激酶(JNK)抑制剂。在基于细胞的模型中,CC-90001对JNK1的选择性是JNK2的12.9倍。CC-90001可用于特发性肺纤维化的研究。

英文名	CC-90001

描述	CC-90001是一种高效、选择性和口服活性的c-junn末端激酶(JNK)抑制剂。在基于细胞的模型中,CC-90001对JNK1的选择性是JNK2的12.9倍。CC-90001可用于特发性肺纤维化的研究。

分子式	C₁₆H₂₇N₅O₂
分子量	321.42
InChIKey	QBBRJRLJWXRSHQ-CKYFFXLPSA-N
SMILES	CC1CCC(Nc2nc(NC(C)(C)C)ncc2C(N)=O)CC1O

实验名称：Inhibition of N-terminal GST-tagged recombinant full length human JNK1 expressed in b...
来源：ChEMBL
靶标：Mitogen-activated protein kinase 8
External Id：CHEMBL5370892

实验名称：Antifibrotic activity against chronic-deficient amino acid-fed Wistar rat model of li...
来源：ChEMBL
靶标：Rattus norvegicus
External Id：CHEMBL4842284

实验名称：Antifibrotic activity against chronic-deficient amino acid-fed Wistar rat model of li...
来源：ChEMBL
靶标：Rattus norvegicus
External Id：CHEMBL4842283

实验名称：Inhibition of LPS-stimulated TNF-alpha release in CD rat model at 30 mg/kg, po treate...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL4842282

实验名称：Inhibition of LPS-stimulated TNF-alpha release in CD rat model at 10 mg/kg, po treate...
来源：ChEMBL
靶标：N/A
External Id：CHEMBL4842281

实验名称：Efflux ratio in human Caco2 cells
来源：ChEMBL
靶标：N/A
External Id：CHEMBL4842286

实验名称：Antifibrotic activity against chronic-deficient amino acid-fed Wistar rat model of li...
来源：ChEMBL
靶标：Rattus norvegicus
External Id：CHEMBL4842285

实验名称：Inhibition of JNK2 (unknown origin) assessed as reduction in phosphorylated ULight-la...
来源：ChEMBL
靶标：Mitogen-activated protein kinase 9
External Id：CHEMBL4842274

实验名称：Inhibition of JNK1 (unknown origin) assessed as reduction in phosphorylated ULight-la...
来源：ChEMBL
靶标：Mitogen-activated protein kinase 8
External Id：CHEMBL4842273

实验名称：Inhibition of human ERG at 30 uM relative to control
来源：ChEMBL
靶标：Potassium voltage-gated channel subfamily H member 2
External Id：CHEMBL4842280

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