Cyclohexanecarboxylic acid, 4-[[1-[5-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-2-pyridinyl]-4-piperidinyl]oxy]-, trans

• 常用名: Cyclohexanecarboxylic acid, 4-[[1-[5-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-2-pyridinyl]-4-piperidinyl]oxy]-, trans
• 英文名: Cyclohexanecarboxylic acid, 4-[[1-[5-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-2-pyridinyl]-4-piperidinyl]oxy]-, trans
• CAS号: 1415571-46-8
• 分子量: 488.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₅H₂₇F₃N₄O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: Cyclohexanecarboxylic acid, 4-[[1-[5-[6-(trifluoromethyl)-1H-benzimidazol-2-yl]-2-pyridinyl]-4-piperidinyl]oxy]-, trans

物理化学性质

• 分子式: C₂₅H₂₇F₃N₄O₃
• 分子量: 488.5
• InChIKey: MCFBUIIRFZBRCU-UHFFFAOYSA-N
• SMILES: O=C(O)C1CCC(OC2CCN(c3ccc(-c4nc5ccc(C(F)(F)F)cc5[nH]4)cn3)CC2)CC1

靶点实验

查看更多实验

实验名称：Inhibition of plasma triglyceride accumulation in mouse at 10 mg/kg, po dosed 2 hrs b... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3386697

实验名称：Inhibition of plasma triglyceride accumulation in Sprague-Dawley rat at 1 mg/kg, po d... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3386698

实验名称：Selectivity index, ratio of Ki for human A2A receptor to KI IC50 for human DGAT1 来源：ChEMBL 靶标：N/A External Id：CHEMBL3386700

实验名称：Unbound fraction in mouse plasma 来源：ChEMBL 靶标：Plasma External Id：CHEMBL3386703

实验名称：Inhibition of plasma triglyceride accumulation in Sprague-Dawley rat at 3 mg/kg, po d... 来源：ChEMBL 靶标：Rattus norvegicus External Id：CHEMBL3386705

实验名称：Unbound fraction in human plasma 来源：ChEMBL 靶标：Plasma External Id：CHEMBL3386704

实验名称：Reduction in cumulative body weight gain in wild type mouse at 10 mg/kg, po dosed dai... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3386709

实验名称：Reduction in cumulative body weight gain in DGAT1 knockout mouse at 10 mg/kg, po dose... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3386711

实验名称：Reduction in food intake in wild type mouse at 10 mg/kg, po dosed daily for 6 days me... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL3386710

实验名称：Inhibition of human ACAT1 at 10 uM 来源：ChEMBL 靶标：Sterol O-acyltransferase 1 External Id：CHEMBL3386695

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