1-(4-(((6-Amino-5-(4-phenoxyphenyl)pyrimidin-4-yl)amino)methyl)-4-hydroxypiperidin-1-yl)prop-2-en-1-one

• 常用名: 1-(4-(((6-Amino-5-(4-phenoxyphenyl)pyrimidin-4-yl)amino)methyl)-4-hydroxypiperidin-1-yl)prop-2-en-1-one
• 英文名: 1-(4-(((6-Amino-5-(4-phenoxyphenyl)pyrimidin-4-yl)amino)methyl)-4-hydroxypiperidin-1-yl)prop-2-en-1-one
• CAS号: 1415821-53-2
• 分子量: 445.5
• 密度: N/A
• 沸点: N/A
• 分子式: C₂₅H₂₇N₅O₃
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 1-(4-(((6-Amino-5-(4-phenoxyphenyl)pyrimidin-4-yl)amino)methyl)-4-hydroxypiperidin-1-yl)prop-2-en-1-one

物理化学性质

• 分子式: C₂₅H₂₇N₅O₃
• 分子量: 445.5
• InChIKey: MCPXHVDMIHIMOC-UHFFFAOYSA-N
• SMILES: C=CC(=O)N1CCC(O)(CNc2ncnc(N)c2-c2ccc(Oc3ccccc3)cc2)CC1

靶点实验

查看更多实验

实验名称：Inhibition of human ERG expressed in HEK293 cells at 10 uM at -80 mV holding potentia... 来源：ChEMBL 靶标：Potassium voltage-gated channel subfamily H member 2 External Id：CHEMBL4375191

实验名称：Enzyme Assay from US Patent US9580449: "Compositions and methods for the production o... 来源：BindingDB 靶标：N/A External Id：BindingDB_802_1

实验名称：Covalent inhibition of N-terminal GST-fused human BTK (2-659(end) amino acids) expres... 来源：ChEMBL 靶标：Tyrosine-protein kinase BTK External Id：CHEMBL4375192

实验名称：Inhibition of BTK in human PBMC cells assessed as reduction in anti-IgM-stimulated CD... 来源：ChEMBL 靶标：Tyrosine-protein kinase BTK External Id：CHEMBL4375195

实验名称：Apparent permeability across apical to basolateral side in human Caco2 cells at 1 uM ... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4375196

实验名称：Efflux ratio in human Caco2 cells 来源：ChEMBL 靶标：N/A External Id：CHEMBL4375197

实验名称：Kinetic solubility of the compound 来源：ChEMBL 靶标：N/A External Id：CHEMBL4375198

实验名称：Intrinsic clearance in human liver microsomes at 1 uM in presence of NADPH measured u... 来源：ChEMBL 靶标：N/A External Id：CHEMBL4375200

实验名称：Inhibition of B cell activation in C57BL/6 mouse at 1 mg/kg, po after 0.25 hr relativ... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4375201

实验名称：Inhibition of B cell activation in C57BL/6 mouse at 1 mg/kg, po after 1 hr relative t... 来源：ChEMBL 靶标：Mus musculus External Id：CHEMBL4375202

共11条，当前第1页，共2页

1

2