(2',5'-bis-O-(tert-butyldimethylsilyl)-beta-ribofuranosyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine

• 常用名: (2',5'-bis-O-(tert-butyldimethylsilyl)-beta-ribofuranosyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine
• 英文名: (2',5'-bis-O-(tert-butyldimethylsilyl)-beta-ribofuranosyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)thymine
• CAS号: 141781-17-1
• 分子量: 589.85000
• 密度: 1.22g/cm3
• 沸点: N/A
• 分子式: C₂₄H₄₃N₃O₈SSi₂
• 熔点: N/A
• 闪点: N/A

名称

• 英文名: 1-[(5R,6R,8R,9R)-4-amino-9-[tert-butyl(dimethyl)silyl]oxy-6-[[tert-butyl(dimethyl)silyl]oxymethyl]-2,2-dioxo-1,7-dioxa-2λ6-thiaspiro[4.4]non-3-en-8-yl]-5-methylpyrimidine-2,4-dione

物理化学性质

• 密度: 1.22g/cm3
• 分子式: C₂₄H₄₃N₃O₈SSi₂
• 分子量: 589.85000
• 精确质量: 589.23100
• PSA: 160.58000
• LogP: 5.24690
• InChIKey: YMSLYTIPSGCZRM-DSPLJNTKSA-N
• SMILES: Cc1cn(C2OC(CO[Si](C)(C)C(C)(C)C)C3(OS(=O)(=O)C=C3N)C2O[Si](C)(C)C(C)(C)C)c(=O)[nH]c1=O
• 折射率: 1.541

靶点实验

查看更多实验

实验名称：Cytotoxicity against human CEM cells after 4 days 来源：ChEMBL 靶标：CCRF-CEM External Id：CHEMBL1832100

实验名称：Antiviral activity against HIV2 ROD infected in human CEM cells assessed as inhibitio... 来源：ChEMBL 靶标：Human immunodeficiency virus 2 External Id：CHEMBL1832099

实验名称：Cytotoxicity against human HuH7 cells after 72 hrs 来源：ChEMBL 靶标：Huh-7 External Id：CHEMBL1832102

实验名称：Antiviral activity against HCV2a JFH1 infected in human Huh7 cells assessed as inhibi... 来源：ChEMBL 靶标：Hepacivirus hominis External Id：CHEMBL1832101

实验名称：Concentration of compound required to inhibit HIV-1(IIIB) induced cytopathicity in CE... 来源：ChEMBL 靶标：CCRF-CEM External Id：CHEMBL834376

实验名称：Antiviral activity against HIV1 harboring reverse transcriptase E138K mutant infected... 来源：ChEMBL 靶标：Human immunodeficiency virus 1 External Id：CHEMBL1832103

实验名称：Concentration of compound required to inhibit HIV-2 (ROD) induced cytopathicity in CE... 来源：ChEMBL 靶标：CCRF-CEM External Id：CHEMBL834377

实验名称：Antiviral activity against HIV2 ROD in CEM cells assessed as inhibition of viral repl... 来源：ChEMBL 靶标：Human immunodeficiency virus 2 External Id：CHEMBL951325

实验名称：Concentration of compound required to inhibit HIV-2 (ROD) induced cytopathicity in MT... 来源：ChEMBL 靶标：MT4 External Id：CHEMBL834473

实验名称：Concentration of compound required to inhibit HIV-1(IIIB) induced cytopathicity in MT... 来源：ChEMBL 靶标：MT4 External Id：CHEMBL834472

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英文别名

• Tsao-T
• C24H43N3O8SSi2
• 2',5'-bis-O-(tert-butyldimethylsilyl)-3'-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide)pyrimidine
• 2,4(1H,3H)-Pyrimidinedione,1-(4-amino-9-(((1,1-dimethylethyl)dimethylsilyl)oxy)-6-((((1,1-dimethylethyl)dimethylsilyl)oxy)methyl)-1,7-dioxa-2-thiaspiro(4,4)non-3-en-8-yl)-5-methyl-,S,S-dioxide. (5R-(5alpha,6beta,8beta,9alpha))
• 3qo9